{"id":34754,"date":"2017-02-21T20:45:48","date_gmt":"2017-02-22T04:45:48","guid":{"rendered":"http:\/\/lifeboat.com\/blog\/2017\/02\/t-cells-support-long-lived-antibody-producing-cells"},"modified":"2017-04-24T18:50:34","modified_gmt":"2017-04-25T01:50:34","slug":"t-cells-support-long-lived-antibody-producing-cells","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2017\/02\/t-cells-support-long-lived-antibody-producing-cells","title":{"rendered":"T cells support long-lived antibody-producing cells"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/t-cells-support-long-lived-antibody-producing-cells.jpg\"><\/a><\/p>\n<p>If you\u2019ve ever wondered how a vaccine given decades ago can still protect against infection, you have your plasma cells to thank. Plasma cells are long-lived B cells that reside in the bone marrow and churn out antibodies against previously encountered vaccines or pathogens.<\/p>\n<p>While <a href=\"https:\/\/medicalxpress.com\/tags\/plasma+cells\/\" rel=\"tag\" class=\"\">plasma cells<\/a> are vital components of the immune system, they can also be a contributor to disease, as is the case in autoimmune diseases, such as lupus and rheumatoid arthritis, and in certain cancers, such as multiple myeloma.<\/p>\n<p>Now, a group led by researchers at the University of Pennsylvania School of Veterinary Medicine, has come to a better understanding of how these cells are maintained. Using a specialized type of microscope that captures the movement and interaction of cells in <a href=\"https:\/\/medicalxpress.com\/tags\/living+organisms\/\" rel=\"tag\" class=\"\">living organisms<\/a>, the scientists observed that, in the <a href=\"https:\/\/medicalxpress.com\/tags\/bone+marrow\/\" rel=\"tag\" class=\"\">bone marrow<\/a>, immune cells called regulatory T cells closely interact with plasma cells and support them. When the T cells aren\u2019t there, plasma cells vanish.<\/p>\n<p><!-- Link: <a href=\"https:\/\/medicalxpress.com\/news\/2017-02-cells-long-lived-antibody-producing.html\">https:\/\/medicalxpress.com\/news\/2017&#45;02-cells-long-lived-...ucing.html<\/a> --><\/p>\n","protected":false},"excerpt":{"rendered":"<p>If you\u2019ve ever wondered how a vaccine given decades ago can still protect against infection, you have your plasma cells to thank. Plasma cells are long-lived B cells that reside in the bone marrow and churn out antibodies against previously encountered vaccines or pathogens. While plasma cells are vital components of the immune system, they [\u2026]<\/p>\n","protected":false},"author":395,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-34754","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/34754","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/395"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=34754"}],"version-history":[{"count":2,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/34754\/revisions"}],"predecessor-version":[{"id":48783,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/34754\/revisions\/48783"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=34754"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=34754"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=34754"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}