{"id":33103,"date":"2017-01-02T11:48:39","date_gmt":"2017-01-02T19:48:39","guid":{"rendered":"http:\/\/lifeboat.com\/blog\/2017\/01\/regenerative-medicine-scientists-have-successfully-engineered-functioning-human-nerves"},"modified":"2017-04-24T19:07:14","modified_gmt":"2017-04-25T02:07:14","slug":"regenerative-medicine-scientists-have-successfully-engineered-functioning-human-nerves","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2017\/01\/regenerative-medicine-scientists-have-successfully-engineered-functioning-human-nerves","title":{"rendered":"Regenerative Medicine: Scientists Have Successfully Engineered Functioning Human Nerves"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/regenerative-medicine-scientists-have-successfully-engineered-functioning-human-nerves.jpg\"><\/a><\/p>\n<p>In a breakthrough for regenerative medicine, scientists have grown intestinal tissues with functional nerves in a laboratory setup using human pluripotent stem cells. The synthesized tissue was used to study <a href=\"http:\/\/www.mayoclinic.org\/diseases-conditions\/hirschsprung's-disease\/home\/ovc-20214664\" target=\"_blank\">Hirschsprung\u2019s disease<\/a>, a congenital condition where nerve cells are missing from the colon, causing complications in passing stool. The research is detailed in <i>Nature Medicine.<\/i><\/p>\n<p>A pluripotent stem cell is a precursor cell to all the other types of cells in the body. In a petri dish, the stem cells were treated in a biochemical bath that triggered the formation into intestinal tissue. The novel part of the study was the construction of a nervous system on the intestinal organoid. The researchers manipulated neural crest cells to grow a system of nerves. By putting together the neural crest cells and the intestinal tissue at the exact time, they successfully grew together into a complex functional system.<\/p>\n<p>The tissues were transplanted into mice. They worked successfully and showed a structure \u201cremarkably similar\u201d to that of a natural human intestine.<\/p>\n<p><!-- Link: <a href=\"https:\/\/futurism.com\/regenerative-medicine-scientists-have-successfully-engineered-functioning-human-nerves\/\">https:\/\/futurism.com\/regenerative-medicine-scientists-have-s...an-nerves\/<\/a> --><\/p>\n","protected":false},"excerpt":{"rendered":"<p>In a breakthrough for regenerative medicine, scientists have grown intestinal tissues with functional nerves in a laboratory setup using human pluripotent stem cells. The synthesized tissue was used to study Hirschsprung\u2019s disease, a congenital condition where nerve cells are missing from the colon, causing complications in passing stool. The research is detailed in Nature Medicine. [\u2026]<\/p>\n","protected":false},"author":413,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,269,47],"tags":[],"class_list":["post-33103","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-life-extension","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/33103","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/413"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=33103"}],"version-history":[{"count":2,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/33103\/revisions"}],"predecessor-version":[{"id":49390,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/33103\/revisions\/49390"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=33103"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=33103"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=33103"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}