{"id":33038,"date":"2016-12-29T00:49:02","date_gmt":"2016-12-29T08:49:02","guid":{"rendered":"http:\/\/lifeboat.com\/blog\/2016\/12\/novel-insights-into-neuronal-activity-dependent-gene-expression"},"modified":"2017-06-04T13:55:15","modified_gmt":"2017-06-04T20:55:15","slug":"novel-insights-into-neuronal-activity-dependent-gene-expression","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2016\/12\/novel-insights-into-neuronal-activity-dependent-gene-expression","title":{"rendered":"Novel Insights Into Neuronal Activity-Dependent Gene Expression"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/novel-insights-into-neuronal-activity-dependent-gene-expression.jpg\"><\/a><\/p>\n<p>Summary: A new study explores how neural activity influences CREB dynamics.<\/p>\n<p>Source: Osaka University.<\/p>\n<p>Neuronal activity mediates the formation of neuronal circuits in the cerebral cortex. These processes are regulated by the transcription factor CREB, which regulates gene expression in neuronal activity-dependent processes. Neuronal activity enhances CREB-mediated transcription but the mechanisms remain unclear. CREB binds to a cAMP response element (CRE) in the promoter region of its target genes. Assembly and disassembly of CREB-CRE interactions control spatiotemporal gene expression in the nucleus. However, how CREB interacts with CRE in activity-dependent mechanisms is not known.<\/p>\n<p><!-- Link: <a href=\"http:\/\/neurosciencenews.com\/creb-gene-neural-activity-5820\/\">http:\/\/neurosciencenews.com\/creb-gene-neural-activity-5820\/<\/a> --><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Summary: A new study explores how neural activity influences CREB dynamics. Source: Osaka University. Neuronal activity mediates the formation of neuronal circuits in the cerebral cortex. These processes are regulated by the transcription factor CREB, which regulates gene expression in neuronal activity-dependent processes. Neuronal activity enhances CREB-mediated transcription but the mechanisms remain unclear. CREB binds [\u2026]<\/p>\n","protected":false},"author":395,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[47],"tags":[],"class_list":["post-33038","post","type-post","status-publish","format-standard","hentry","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/33038","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/395"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=33038"}],"version-history":[{"count":3,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/33038\/revisions"}],"predecessor-version":[{"id":65479,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/33038\/revisions\/65479"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=33038"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=33038"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=33038"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}