{"id":32714,"date":"2016-12-15T21:02:52","date_gmt":"2016-12-16T05:02:52","guid":{"rendered":"http:\/\/lifeboat.com\/blog\/2016\/12\/new-structure-shows-how-cells-assemble-protein-making-machinery"},"modified":"2017-04-24T19:12:02","modified_gmt":"2017-04-25T02:12:02","slug":"new-structure-shows-how-cells-assemble-protein-making-machinery","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2016\/12\/new-structure-shows-how-cells-assemble-protein-making-machinery","title":{"rendered":"New structure shows how cells assemble protein-making machinery"},"content":{"rendered":"<p style=\"padding-right: 20px\"><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/new-structure-shows-how-cells-assemble-protein-making-machinery.jpg\"><\/a><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" style=\"display:none;\" class=\"alignright\" src=\"https:\/\/lifeboat.com\/blog.images\/new-structure-shows-how-cells-assemble-protein-making-machinery.jpg\" alt=\"klinge_processome\" width=\"700\" height=\"650\" srcset=\"https:\/\/lifeboat.com\/blog.images\/new-structure-shows-how-cells-assemble-protein-making-machinery.jpg 700w, http:\/\/newswire.rockefeller.edu\/wp-content\/uploads\/2016\/12\/Klinge_processome-300x279.jpg 300w\" sizes=\"auto, (max-width: 700px)  100vw, 700px\" \/>Scientists at The Rockefeller University have created the most detailed three-dimensional images to date of an important step in the process by which cells make the nano-machines responsible for producing all-important protein. The results, described December 15 in Science, are prompting the researchers to re-evaluate how they envision this early phase in the construction of ribosomes.<\/p>\n<p>\u201cThe structure they determined, shown above, belongs to a particle formally called the \u201csmall subunit processome.\u201d Before this particle can fulfill its destiny to become the smaller half of a complete ribosome, the RNA within it needs to be folded, tweaked, and cut.<\/p>\n<p>\u201cInitially, we thought of the small subunit processome as a product on an assembly line, with molecular workers arriving from outside, much like the robots that would put together a car. But that analogy no longer appears apt,\u201d says senior author <a href=\"http:\/\/www.rockefeller.edu\/research\/faculty\/labheads\/SebastianKlinge\/#content\">Sebastian Klinge<\/a>, head of the Laboratory of Protein and Nucleic Acid Chemistry.<\/p>\n<p><!-- Link: <a href=\"http:\/\/newswire.rockefeller.edu\/2016\/12\/15\/new-structure-shows-how-cells-assemble-protein-making-machinery\/\">http:\/\/newswire.rockefeller.edu\/2016\/12\/15\/new-structure-sho...machinery\/<\/a> --><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Scientists at The Rockefeller University have created the most detailed three-dimensional images to date of an important step in the process by which cells make the nano-machines responsible for producing all-important protein. The results, described December 15 in Science, are prompting the researchers to re-evaluate how they envision this early phase in the construction of [\u2026]<\/p>\n","protected":false},"author":395,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[19,4,48,6],"tags":[],"class_list":["post-32714","post","type-post","status-publish","format-standard","hentry","category-chemistry","category-nanotechnology","category-particle-physics","category-robotics-ai"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/32714","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/395"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=32714"}],"version-history":[{"count":3,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/32714\/revisions"}],"predecessor-version":[{"id":49467,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/32714\/revisions\/49467"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=32714"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=32714"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=32714"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}