{"id":32461,"date":"2016-12-07T07:48:08","date_gmt":"2016-12-07T15:48:08","guid":{"rendered":"http:\/\/lifeboat.com\/blog\/2016\/12\/protein-that-promotes-cell-suicide-could-revolutionise-eye-cancer-treatment"},"modified":"2017-06-04T13:59:38","modified_gmt":"2017-06-04T20:59:38","slug":"protein-that-promotes-cell-suicide-could-revolutionise-eye-cancer-treatment","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2016\/12\/protein-that-promotes-cell-suicide-could-revolutionise-eye-cancer-treatment","title":{"rendered":"Protein that promotes \u2018cell-suicide\u2019 could revolutionise eye cancer treatment"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/protein-that-promotes-cell-suicide-could-revolutionise-eye-cancer-treatment.jpg\"><\/a><\/p>\n<p>More progress with cancer and using a similar approach to senolytics, no surprise really as cancer and senescent cell share a lot of common ground and approach that work with one may well work with the other if they are aimed at inducing apoptosis.<\/p>\n<hr>\n<p>Apoptosis, or <a href=\"http:\/\/medicalxpress.com\/tags\/programmed+cell+death\/\" rel=\"tag\" class=\"\">programmed cell death<\/a>, is a rapid and irreversible process to efficiently eliminate dysfunctional cells. A hallmark of cancer is the ability of malignant cells to evade apoptosis.<\/p>\n<p>Dr Luminita Paraoan, from the University\u2019s Department of Eye and Vision Science in the Institute of Ageing and Chronic Disease, has published new findings in the <i>British Journal of Cancer<\/i> that identify the requirement of a protein called p63 for the initiation of apoptosis in UM.<\/p>\n<p>Chromosome 3 is one of the 23 pairs of chromosomes in humans. People normally have two copies of each chromosome. One part of chromosome 3 contains the gene for the protein p63. Unfortunately people with aggressive (resistant to apoptosis) UM do not have this part and therefore do not have the p63 protein.<\/p>\n<p><!-- Link: <a href=\"http:\/\/medicalxpress.com\/news\/2016-12-protein-cell-suicide-revolutionise-eye-cancer.html\">http:\/\/medicalxpress.com\/news\/2016&#45;12-protein-cell-suici...ancer.html<\/a> --><\/p>\n","protected":false},"excerpt":{"rendered":"<p>More progress with cancer and using a similar approach to senolytics, no surprise really as cancer and senescent cell share a lot of common ground and approach that work with one may well work with the other if they are aimed at inducing apoptosis. Apoptosis, or programmed cell death, is a rapid and irreversible process [\u2026]<\/p>\n","protected":false},"author":370,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,269],"tags":[],"class_list":["post-32461","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-life-extension"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/32461","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/370"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=32461"}],"version-history":[{"count":2,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/32461\/revisions"}],"predecessor-version":[{"id":65640,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/32461\/revisions\/65640"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=32461"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=32461"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=32461"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}