{"id":31951,"date":"2016-11-15T13:49:31","date_gmt":"2016-11-15T21:49:31","guid":{"rendered":"http:\/\/lifeboat.com\/blog\/2016\/11\/new-protein-provides-critical-link-between-aging-and-age-dependent-disease"},"modified":"2017-04-24T19:19:44","modified_gmt":"2017-04-25T02:19:44","slug":"new-protein-provides-critical-link-between-aging-and-age-dependent-disease","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2016\/11\/new-protein-provides-critical-link-between-aging-and-age-dependent-disease","title":{"rendered":"New protein provides critical link between aging and age-dependent disease"},"content":{"rendered":"<p><a class=\"blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/new-protein-provides-critical-link-between-aging-and-age-dependent-disease2.jpg\"><\/a><\/p>\n<p>New hope for age related macular degeneration.<\/p>\n<hr>\n<p>The discovery of a novel protein that links aging and age-dependent retinal diseases could lead to potential new treatments for conditions that cause sight loss in later life.<\/p>\n<p>In a study in mice, to be published in the journal <i>eLife<\/i>, researchers from the University of Wisconsin-Madison reveal that Transmembrane 135 (Tmem135) regulates retinal aging, and that mutations in the protein result in age-dependent disease.<\/p>\n<p>Tmem135 has previously been associated with fat storage and long life in the roundworm <i>Caenorhabditis elegans<\/i>, but its molecular function has never been characterized clearly. The new study shows that irregular levels of the protein lead to symptoms of a common age-related retinal disease called macular degeneration.<\/p>\n<p><!-- Link: <a href=\"http:\/\/medicalxpress.com\/news\/2016-11-protein-critical-link-aging-age-dependent.html\">http:\/\/medicalxpress.com\/news\/2016&#45;11-protein-critical-l...ndent.html<\/a> --><\/p>\n","protected":false},"excerpt":{"rendered":"<p>New hope for age related macular degeneration. The discovery of a novel protein that links aging and age-dependent retinal diseases could lead to potential new treatments for conditions that cause sight loss in later life. In a study in mice, to be published in the journal eLife, researchers from the University of Wisconsin-Madison reveal that [\u2026]<\/p>\n","protected":false},"author":370,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,269],"tags":[],"class_list":["post-31951","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-life-extension"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/31951","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/370"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=31951"}],"version-history":[{"count":2,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/31951\/revisions"}],"predecessor-version":[{"id":49595,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/31951\/revisions\/49595"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=31951"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=31951"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=31951"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}