{"id":31624,"date":"2016-11-02T19:48:18","date_gmt":"2016-11-03T02:48:18","guid":{"rendered":"http:\/\/lifeboat.com\/blog\/2016\/11\/synthetic-virus-created-to-treat-cancer-in-dogs"},"modified":"2017-06-04T09:16:57","modified_gmt":"2017-06-04T16:16:57","slug":"synthetic-virus-created-to-treat-cancer-in-dogs","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2016\/11\/synthetic-virus-created-to-treat-cancer-in-dogs","title":{"rendered":"Synthetic Virus Created to Treat Cancer in Dogs"},"content":{"rendered":"<p style=\"padding-right: 20px\"><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/synthetic-virus-created-to-treat-cancer-in-dogs.jpg\"><\/a><\/p>\n<p>2 November 2016. Two companies partnering with Auburn University developed a synthetic virus to find and destroy tumor cells in a type of bone cancer in dogs. Financial and intellectual property aspects of the agreement between synthetic gene company <a href=\"https:\/\/blog.gen9bio.com\/about-us\/news-events\/press-releases\/autodesk-auburn-gen9-cancer-research\">Gen9<\/a> in Cambridge, Massachusetts, design systems developer Autodesk Inc. in San Rafael, California, and Auburn University College of Veterinary Medicine in Alabama were not disclosed.<\/p>\n<p>The research team created a synthetic version of <a href=\"http:\/\/www.merck-animal-health-usa.com\/diseases\/130_19178_2\/ProductDetails_130_114017.aspx\">canine adenovirus type 2<\/a>, or CAV2, a virus usually associated with hepatitis in dogs. In this case, the synthetic CAV-2 virus is designed as an <a href=\"http:\/\/www.nature.com\/nrd\/journal\/v14\/n9\/full\/nrd4663.html\">oncolytic virus<\/a> that finds and attacks cancer cells, while leaving healthy cells and tissue intact. The genome in the organism is believed to be the longest in a functional virus synthesized for cancer research, with about 34,000 base pairs of nucleic acids. The <a href=\"https:\/\/www.genome.gov\/11006943\/human-genome-project-completion-frequently-asked-questions\/\">human genome<\/a>, by comparison, has about 3 billion base pairs.<\/p>\n<p>The <a href=\"https:\/\/www.gen9bio.com\/technology\/biofab-for-gene-synthesis\">technology<\/a> provided by Gen9 in this project makes it possible to eventually produce synthetic therapeutic viruses tailored for specific patients. Gen9 offers customized gene synthesis and is developing a library of synthesized proteins and antibodies. One of the 4 year-old company\u2019s founders is <a href=\"https:\/\/www.gen9bio.com\/about-us\/our-founders\">George Church<\/a>, a geneticist at Harvard Medical School and <a href=\"http:\/\/arep.med.harvard.edu\/gmc\/tech.html\">serial entrepreneur<\/a>. In August 2016, as reported in <a href=\"http:\/\/sciencebusiness.technewslit.com\/?p=29465\">Science &amp; Enterprise<\/a>, Church and colleagues, including those from Gen9, developed a synthetic <em>E. coli<\/em> bacteria genome with redundant DNA components removed.<\/p>\n<p><!-- Link: <a href=\"http:\/\/sciencebusiness.technewslit.com\/?p=29846\">http:\/\/sciencebusiness.technewslit.com\/?p=29846<\/a> --><\/p>\n","protected":false},"excerpt":{"rendered":"<p>2 November 2016. Two companies partnering with Auburn University developed a synthetic virus to find and destroy tumor cells in a type of bone cancer in dogs. Financial and intellectual property aspects of the agreement between synthetic gene company Gen9 in Cambridge, Massachusetts, design systems developer Autodesk Inc. in San Rafael, California, and Auburn University [\u2026]<\/p>\n","protected":false},"author":395,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,45,412],"tags":[],"class_list":["post-31624","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-finance","category-genetics"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/31624","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/395"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=31624"}],"version-history":[{"count":2,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/31624\/revisions"}],"predecessor-version":[{"id":59872,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/31624\/revisions\/59872"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=31624"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=31624"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=31624"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}