{"id":31376,"date":"2016-10-25T12:48:02","date_gmt":"2016-10-25T19:48:02","guid":{"rendered":"http:\/\/lifeboat.com\/blog\/2016\/10\/nanofiber-coating-prevents-infections-of-prosthetic-joints"},"modified":"2017-04-26T13:29:39","modified_gmt":"2017-04-26T20:29:39","slug":"nanofiber-coating-prevents-infections-of-prosthetic-joints","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2016\/10\/nanofiber-coating-prevents-infections-of-prosthetic-joints","title":{"rendered":"Nanofiber Coating Prevents Infections of Prosthetic Joints"},"content":{"rendered":"

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A titanium implant (blue) without a nanofiber coating in the femur of a mouse. Bacteria are shown in red and responding immune cells in yellow. Courtesy of Lloyd Miller\/Johns Hopkins Medicine<\/p>\n

In a proof-of-concept study with mice, scientists at The Johns Hopkins University show that a novel coating they made with antibiotic-releasing nanofibers has the potential to better prevent at least some serious bacterial infections related to total joint replacement surgery. A report on the study, published online the week of Oct. 24 in Proceedings of the National Academy of Sciences, was conducted on the rodents\u2019 knee joints, but, the researchers say, the technology would have \u201cbroad applicability\u201d in the use of orthopedic prostheses, such as hip and knee total joint replacements, as well pacemakers, stents and other implantable medical devices. In contrast to other coatings in development, the researchers report the new material can release multiple antibiotics in a strategically timed way for an optimal effect.<\/p>\n

\u201cWe can potentially coat any metallic implant that we put into patients, from prosthetic joints, rods, screws and plates to pacemakers, implantable defibrillators and dental hardware,\u201d says co-senior study author Lloyd S. Miller, MD, PhD, an associate professor of dermatology and orthopedic surgery at the Johns Hopkins University School of Medicine.<\/p>\n

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A titanium implant (blue) without a nanofiber coating in the femur of a mouse. Bacteria are shown in red and responding immune cells in yellow. Courtesy of Lloyd Miller\/Johns Hopkins Medicine In a proof-of-concept study with mice, scientists at The Johns Hopkins University show that a novel coating they made with antibiotic-releasing nanofibers has the [\u2026]<\/p>\n","protected":false},"author":394,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,1499],"tags":[],"class_list":["post-31376","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-cyborgs"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/31376","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/394"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=31376"}],"version-history":[{"count":3,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/31376\/revisions"}],"predecessor-version":[{"id":56808,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/31376\/revisions\/56808"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=31376"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=31376"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=31376"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}