{"id":25899,"date":"2016-05-19T22:32:36","date_gmt":"2016-05-20T05:32:36","guid":{"rendered":"http:\/\/lifeboat.com\/blog\/2016\/05\/mechanism-that-reduces-effect-of-cocaine-on-brain-discovered"},"modified":"2017-04-26T13:17:02","modified_gmt":"2017-04-26T20:17:02","slug":"mechanism-that-reduces-effect-of-cocaine-on-brain-discovered","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2016\/05\/mechanism-that-reduces-effect-of-cocaine-on-brain-discovered","title":{"rendered":"Mechanism that reduces effect of cocaine on brain discovered"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/mechanism-that-reduces-effect-of-cocaine-on-brain-discovered.jpg\"><\/a><\/p>\n<p>Very promising. Wonder how effective it is with Prescription Med. Addictions.<\/p>\n<hr>\n<p>A type of brain cell known as microglia plays a key role in reducing the effects of cocaine in the brain, according to a major study by a team from the Research Institute of the McGill University Health Centre (RI-MUHC) in Montreal.<\/p>\n<p>The discovery, published in the journal <i>Neuron<\/i>, establishes for the first time that microglia can diminish the adverse changes to neural circuitry brought on by the chronic use of <a href=\"http:\/\/medicalxpress.com\/tags\/cocaine\/\" rel=\"tag\" class=\"\">cocaine<\/a> and has significant implications for developing an effective treatment for addiction.<\/p>\n<p>Microglia may not be as well known as neurons, the <a href=\"http:\/\/medicalxpress.com\/tags\/brain+cells\/\" rel=\"tag\" class=\"\">brain cells<\/a> that relay messages, but they have many important functions. They constantly monitor their environment, and can act to maintain normal <a href=\"http:\/\/medicalxpress.com\/tags\/brain\/\" rel=\"tag\" class=\"\">brain<\/a> functioning. When they find something amiss, they can produce molecules that instruct neurons to make adaptive changes to their connections. One such example is the inflammatory molecule known as <a href=\"http:\/\/medicalxpress.com\/tags\/tumor+necrosis+factor\/\" rel=\"tag\" class=\"\">tumor necrosis factor<\/a> (TNF).<\/p>\n<p><!-- Link: <a href=\"http:\/\/m.medicalxpress.com\/news\/2016-05-mechanism-effect-cocaine-brain.html\">http:\/\/m.medicalxpress.com\/news\/2016&#45;05-mechanism-effect-cocaine-brain.html<\/a> --><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Very promising. Wonder how effective it is with Prescription Med. Addictions. A type of brain cell known as microglia plays a key role in reducing the effects of cocaine in the brain, according to a major study by a team from the Research Institute of the McGill University Health Centre (RI-MUHC) in Montreal. The discovery, [\u2026]<\/p>\n","protected":false},"author":395,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1495,47],"tags":[],"class_list":["post-25899","post","type-post","status-publish","format-standard","hentry","category-health","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/25899","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/395"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=25899"}],"version-history":[{"count":3,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/25899\/revisions"}],"predecessor-version":[{"id":56523,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/25899\/revisions\/56523"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=25899"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=25899"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=25899"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}