{"id":25637,"date":"2016-05-12T20:01:38","date_gmt":"2016-05-13T03:01:38","guid":{"rendered":"http:\/\/lifeboat.com\/blog\/2016\/05\/scientists-prove-effectiveness-of-gene-editing-system-in-eliminating-hiv-from-dna-of-cd4-t-cells"},"modified":"2017-04-24T20:53:27","modified_gmt":"2017-04-25T03:53:27","slug":"scientists-prove-effectiveness-of-gene-editing-system-in-eliminating-hiv-from-dna-of-cd4-t-cells","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2016\/05\/scientists-prove-effectiveness-of-gene-editing-system-in-eliminating-hiv-from-dna-of-cd4-t-cells","title":{"rendered":"Scientists prove effectiveness of gene editing system in eliminating HIV from DNA of CD4+ T-cells"},"content":{"rendered":"

<\/a><\/p>\n

Hope for HIV patients.<\/p>\n

\n

In 2014, a team of researchers in the Lewis Katz School of Medicine at Temple University became the first to successfully eliminate the HIV-1 virus from cultured human cells. Fewer than two years later, the team has made further strides in its research by eliminating the virus from the genome of human T-cells using the specialized gene editing system they designed.<\/p>\n

In a new study published in Scientific Reports<\/i>, the researchers show that the method can both effectively and safely eliminate the virus from the DNA of human cells grown in culture.<\/p>\n

How this research differs<\/b> In previous work, the team\u2014led by Kamel Khalili, professor and chair of the Department of Neuroscience at Temple\u2014had demonstrated the ability of their technology to snip out HIV-1 DNA from normal human cells. The newest findings used that same technology to snip out the virus from latently and productively infected CD4+ T-cells, which host the virus in persons infected with HIV.<\/p>\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

Hope for HIV patients. In 2014, a team of researchers in the Lewis Katz School of Medicine at Temple University became the first to successfully eliminate the HIV-1 virus from cultured human cells. Fewer than two years later, the team has made further strides in its research by eliminating the virus from the genome of [\u2026]<\/p>\n","protected":false},"author":395,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1902,11],"tags":[],"class_list":["post-25637","post","type-post","status-publish","format-standard","hentry","category-bioengineering","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/25637","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/395"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=25637"}],"version-history":[{"count":2,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/25637\/revisions"}],"predecessor-version":[{"id":50517,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/25637\/revisions\/50517"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=25637"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=25637"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=25637"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}