{"id":247446,"date":"2026-11-15T12:14:20","date_gmt":"2026-11-15T18:14:20","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/11\/new-transplant-approach-resets-the-immune-system-to-stop-type-1-diabetes"},"modified":"2026-11-15T12:14:20","modified_gmt":"2026-11-15T18:14:20","slug":"new-transplant-approach-resets-the-immune-system-to-stop-type-1-diabetes","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/11\/new-transplant-approach-resets-the-immune-system-to-stop-type-1-diabetes","title":{"rendered":"New transplant approach resets the immune system to stop Type 1 diabetes"},"content":{"rendered":"\n<p>A combination blood stem cell and pancreatic islet cell transplant from an immunologically mismatched donor completely prevented or cured Type 1 diabetes in mice in a study by Stanford Medicine researchers. Type 1 diabetes arises when the immune system mistakenly destroys insulin-producing islet cells in the pancreas.<\/p>\n<p>None of the animals developed graft-versus-host disease \u2014 in which the immune system arising from the donated blood stem cells attacks healthy tissue in the recipient \u2014 and the destruction of islet cells by the native host immune system was halted. After the transplants, the animals did not require the use of the immune suppressive drugs or insulin for the duration of the six-month experiment.<\/p>\n<blockquote><p>The possibility of translating these findings into humans is very exciting. The key steps in our study \u2014 which result in animals with a hybrid immune system containing cells from both the donor and the recipient \u2014 are already being used in the clinic for other conditions. We believe this approach will be transformative for people with Type 1 diabetes or other autoimmune diseases, as well as for those who need solid organ transplants.<\/p><\/blockquote>\n","protected":false},"excerpt":{"rendered":"<p>A combination blood stem cell and pancreatic islet cell transplant from an immunologically mismatched donor completely prevented or cured Type 1 diabetes in mice in a study by Stanford Medicine researchers. Type 1 diabetes arises when the immune system mistakenly destroys insulin-producing islet cells in the pancreas. None of the animals developed graft-versus-host disease \u2014 [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-247446","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/247446","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=247446"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/247446\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=247446"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=247446"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=247446"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}