{"id":247352,"date":"2026-11-14T11:20:35","date_gmt":"2026-11-14T17:20:35","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/11\/leukemia-drug-shows-potential-against-metastatic-her2-positive-breast-cancer"},"modified":"2026-11-14T11:20:35","modified_gmt":"2026-11-14T17:20:35","slug":"leukemia-drug-shows-potential-against-metastatic-her2-positive-breast-cancer","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/11\/leukemia-drug-shows-potential-against-metastatic-her2-positive-breast-cancer","title":{"rendered":"Leukemia Drug Shows Potential Against Metastatic HER2-Positive Breast Cancer"},"content":{"rendered":"\n<p>DURHAM, N.C. \u2013 In animal studies led by researchers at <a href=\"http:\/\/www.dukecancerinstitute.org\/\"> Duke Cancer Institute<\/a>, a drug approved to treat leukemia successfully disrupted the ability of HER2-positive breast cancer tumors from colonizing the brain.<\/p>\n<p>The finding, appearing online Aug. 30 in the journal Cell Reports, provides evidence for human trials and suggests a potential new approach to derail one of the main ways that breast cancer turns deadly.<\/p>\n<p>\u201cWe have made huge strides in treating HER2-positive breast cancers, but when tumors escape the therapies, they often metastasize to the brain,\u201d said senior author <a href=\"https:\/\/sites.duke.edu\/pendergastlab\/\"> Ann Marie Pendergast<\/a>, Ph.D., professor and vice chair of the <a href=\"https:\/\/medschool.duke.edu\/departments-centers-institutes\/department-pharmacology-and-cancer-biology\"> Department of Pharmacology and Cancer Biology<\/a> at Duke University School of Medicine.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>DURHAM, N.C. \u2013 In animal studies led by researchers at Duke Cancer Institute, a drug approved to treat leukemia successfully disrupted the ability of HER2-positive breast cancer tumors from colonizing the brain. The finding, appearing online Aug. 30 in the journal Cell Reports, provides evidence for human trials and suggests a potential new approach to [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,47],"tags":[],"class_list":["post-247352","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/247352","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=247352"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/247352\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=247352"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=247352"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=247352"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}