{"id":247149,"date":"2026-11-11T23:29:21","date_gmt":"2026-11-12T05:29:21","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/11\/new-method-maps-dna-folding-and-epigenetic-marks-in-single-cells"},"modified":"2026-11-11T23:29:21","modified_gmt":"2026-11-12T05:29:21","slug":"new-method-maps-dna-folding-and-epigenetic-marks-in-single-cells","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/11\/new-method-maps-dna-folding-and-epigenetic-marks-in-single-cells","title":{"rendered":"New method maps DNA folding and epigenetic marks in single cells"},"content":{"rendered":"\n<p>A new experimental procedure developed by researchers at Yale School of Medicine could help scientists better understand how DNA structure influences disease and development.<\/p>\n<p>DNA underpins nearly all cellular functions. Which genes a cell uses depends on the structure of DNA in the nucleus\u2014shaped by both DNA\u2019s three-dimensional (3D) folding and the chemical modifications to DNA and its associated proteins called epigenetic marks.<\/p>\n<p>Understanding the relationship between the 3D genome and epigenetics has implications for DNA function and disease. However, most methods struggle to combine these two factors.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A new experimental procedure developed by researchers at Yale School of Medicine could help scientists better understand how DNA structure influences disease and development. DNA underpins nearly all cellular functions. Which genes a cell uses depends on the structure of DNA in the nucleus\u2014shaped by both DNA\u2019s three-dimensional (3D) folding and the chemical modifications to [\u2026]<\/p>\n","protected":false},"author":427,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,19,412],"tags":[],"class_list":["post-247149","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-chemistry","category-genetics"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/247149","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/427"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=247149"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/247149\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=247149"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=247149"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=247149"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}