{"id":247122,"date":"2026-11-11T19:19:18","date_gmt":"2026-11-12T01:19:18","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/11\/the-structural-basis-of-il-36r-proinflammatory-signaling-mediated-by-il-36%ce%b3-and-il-37"},"modified":"2026-11-11T19:19:18","modified_gmt":"2026-11-12T01:19:18","slug":"the-structural-basis-of-il-36r-proinflammatory-signaling-mediated-by-il-36%ce%b3-and-il-37","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/11\/the-structural-basis-of-il-36r-proinflammatory-signaling-mediated-by-il-36%ce%b3-and-il-37","title":{"rendered":"The structural basis of IL-36R proinflammatory signaling mediated by IL-36\u03b3 and IL-37"},"content":{"rendered":"\n<p>Structural insights reveal how IL-36R is activated by distinct cytokines and antagonized by spesolimab.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Structural insights reveal how IL-36R is activated by distinct cytokines and antagonized by spesolimab.<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"class_list":["post-247122","post","type-post","status-publish","format-standard","hentry","category-futurism"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/247122","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=247122"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/247122\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=247122"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=247122"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=247122"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}