Researchers at Texas A&M University have cracked a problem that has limited biological imaging for years: seeing fine cellular detail while looking deep inside living tissue. The new microscopy technique resolves structures smaller than 100 nanometers, roughly a thousand times thinner than a human hair, without giving up the ability to image deep into intact samples.<\/p>\n
The team, led by Aart Verhoef, Ph.D., assistant professor of biophotonics in the Department of Soil and Crop Sciences in the Texas A&M College of Agriculture and Life Sciences and joint professor in the Department of Physics and Astronomy, published<\/a> the findings in the Journal of Biomedical Optics.<\/p>\n Their method, called 2PE-ISM-SOFI, short for two-photon excited image scanning microscopy combined with super-resolution optical fluctuation imaging, layers two established techniques onto a standard two-photon microscope to sharpen its resolution without shrinking its reach.<\/p>\n","protected":false},"excerpt":{"rendered":" Researchers at Texas A&M University have cracked a problem that has limited biological imaging for years: seeing fine cellular detail while looking deep inside living tissue. The new microscopy technique resolves structures smaller than 100 nanometers, roughly a thousand times thinner than a human hair, without giving up the ability to image deep into intact [\u2026]<\/p>\n","protected":false},"author":427,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-247092","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/247092","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/427"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=247092"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/247092\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=247092"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=247092"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=247092"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}