{"id":247051,"date":"2026-11-10T22:13:09","date_gmt":"2026-11-11T04:13:09","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/11\/preclinical-findings-show-experimental-drug-eliminates-75-of-aggressive-pancreatic-tumors-and-enhances-immune-system-memory-to-fight-other-cancers"},"modified":"2026-11-10T22:13:09","modified_gmt":"2026-11-11T04:13:09","slug":"preclinical-findings-show-experimental-drug-eliminates-75-of-aggressive-pancreatic-tumors-and-enhances-immune-system-memory-to-fight-other-cancers","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/11\/preclinical-findings-show-experimental-drug-eliminates-75-of-aggressive-pancreatic-tumors-and-enhances-immune-system-memory-to-fight-other-cancers","title":{"rendered":"Preclinical Findings Show Experimental Drug Eliminates 75% of Aggressive Pancreatic Tumors and Enhances Immune System Memory to Fight Other Cancers"},"content":{"rendered":"\n<p><strong>Newswise \u2014 CLEVELAND, Ohio<\/strong> \u2014 Many solid tumors, including many cancers of the pancreas, breast, colon and lung, protect themselves with a dense wall of scar-like tissue. That wall keeps the immune system\u2019s cancer killing T cells out. It is a major reason why immunotherapy drugs, which have transformed treatment for some patients, help only a minority of people with solid tumors.<\/p>\n<p><a href=\"https:\/\/www.cell.com\/cancer-cell\/fulltext\/S1535-6108(26)00473-3\">A study published today in <em>Cancer Cell<\/em><\/a> describes an experimental drug that breaks down this barrier from inside the tumor and lets T cells in to attack. In mice, the drug cleared aggressive pancreatic tumors, stopped breast cancer from spreading, and left the animals with long-lasting immune memory. That memory protected against new tumors, including some different types of cancer.<\/p>\n<p>The international study was led by Dr. Seong-Jin Kim and his team of scientists at MedPacto, Inc., in Seoul, Korea. Co-author John J. Letterio, MD, PhD, is Director of the Angie Fowler Adolescent and Young Adult Cancer Institute at University Hospitals Rainbow Babies &amp; Children\u2019s Hospital and Director of the Developmental Therapeutics Program at Case Comprehensive Cancer Center, Case Western Reserve University.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Newswise \u2014 CLEVELAND, Ohio \u2014 Many solid tumors, including many cancers of the pancreas, breast, colon and lung, protect themselves with a dense wall of scar-like tissue. That wall keeps the immune system\u2019s cancer killing T cells out. It is a major reason why immunotherapy drugs, which have transformed treatment for some patients, help only [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-247051","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/247051","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=247051"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/247051\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=247051"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=247051"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=247051"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}