Bones may not only shape how a body looks, but also how it ages. Researchers investigating the well-known antiaging effects of physical activity have found in mice that bones may be a veritable fountain of youth, dribbling out proteins that slow aging, keep the body healthy, and extend life span.<\/p>\n
The rodent results, published last week in Cell Metabolism<\/a><\/em>, show mechanical strain on the skeleton\u2014the pushing, pulling, and twisting that normally happen during exercise and other forms of physical activity\u2014triggers force-sensing bone cells called osteocytes to secrete the antiaging chemicals. Indeed, the research team could extend mouse lives by nearly 3 months\u2014the equivalent<\/a> of about nine human years\u2014just by gently squeezing their leg bones.<\/p>\n \u201cBone is not just a passive scaffold; it is an active, mechanically responsive organ that helps set the pace of aging throughout the body,\u201d says Xiaochun Bai, a leader of the study and a bone biologist at Southern Medical University. \u201cFor the first time, we demonstrated the role of bone \u2018mechanosensing\u2019 in systemic aging.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":" Bones may not only shape how a body looks, but also how it ages. Researchers investigating the well-known antiaging effects of physical activity have found in mice that bones may be a veritable fountain of youth, dribbling out proteins that slow aging, keep the body healthy, and extend life span. The rodent results, published last [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,19,269],"tags":[],"class_list":["post-246939","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-chemistry","category-life-extension"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/246939","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=246939"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/246939\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=246939"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=246939"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=246939"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}