{"id":246930,"date":"2026-11-09T10:29:34","date_gmt":"2026-11-09T16:29:34","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/11\/why-obesity-affects-males-and-females-differently"},"modified":"2026-11-09T10:29:34","modified_gmt":"2026-11-09T16:29:34","slug":"why-obesity-affects-males-and-females-differently","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/11\/why-obesity-affects-males-and-females-differently","title":{"rendered":"Why obesity affects males and females differently"},"content":{"rendered":"\n<p>University of California, Riverside, scientists have an explanation for why males and females respond differently to obesity. They <a href=\"https:\/\/academic.oup.com\/pnasnexus\/article\/5\/11\/pgag365\/8995448\" target=\"_blank\">report<\/a> in <i>PNAS Nexus<\/i> that certain immune cell populations in fat tissue may protect against obesity-related inflammation while others may contribute to harmful metabolic changes. They found these immune cells, called eosinophils and traditionally associated with asthma and allergies, behave differently in males and females.<\/p>\n<p>The research, done in mice and led by biomedical scientists Meera Nair and Adam Godzik, challenges the conventional view that eosinophils are relatively uniform immune cells with a limited range of functions and suggests new possibilities for developing targeted treatments.<\/p>\n<p>Using high-resolution single-cell sequencing, the team identified six distinct eosinophil populations in adipose (fat) tissue, each with different gene-expression patterns and potential functions.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>University of California, Riverside, scientists have an explanation for why males and females respond differently to obesity. They report in PNAS Nexus that certain immune cell populations in fat tissue may protect against obesity-related inflammation while others may contribute to harmful metabolic changes. They found these immune cells, called eosinophils and traditionally associated with asthma [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,1495],"tags":[],"class_list":["post-246930","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-health"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/246930","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=246930"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/246930\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=246930"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=246930"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=246930"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}