{"id":246905,"date":"2026-11-09T06:13:12","date_gmt":"2026-11-09T12:13:12","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/11\/dry-eye-disease-beyond-tear-deficiency"},"modified":"2026-11-09T06:13:12","modified_gmt":"2026-11-09T12:13:12","slug":"dry-eye-disease-beyond-tear-deficiency","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/11\/dry-eye-disease-beyond-tear-deficiency","title":{"rendered":"Dry Eye Disease: Beyond Tear Deficiency"},"content":{"rendered":"\n<p><a href=\"https:\/\/www.nei.nih.gov\/eye-health-information\/eye-conditions-and-diseases\/dry-eye\" rel=\"nofollow\" target=\"_blank\">Dry eye<\/a> disease (DED) is a multifactorial ocular surface disease characterized by loss of tear film homeostasis, with tear film instability, hyperosmolarity, inflammation, ocular surface damage, and neurosensory abnormalities contributing to symptoms and visual disturbance. This <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10934010\/\" rel=\"nofollow\" target=\"_blank\">disease<\/a> may involve aqueous-deficient, evaporative, or mixed mechanisms.<\/p>\n<p>Medscape spoke with Christopher J. Rapuano, MD, chief of the Cornea Service at Wills Eye Hospital and professor of ophthalmology at Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, about reframing DED within the broader context of ocular surface disease, evaluating alternative causes of ocular discomfort, and selecting management according to the underlying disorder.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Dry eye disease (DED) is a multifactorial ocular surface disease characterized by loss of tear film homeostasis, with tear film instability, hyperosmolarity, inflammation, ocular surface damage, and neurosensory abnormalities contributing to symptoms and visual disturbance. This disease may involve aqueous-deficient, evaporative, or mixed mechanisms. Medscape spoke with Christopher J. Rapuano, MD, chief of the Cornea [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,1509],"tags":[],"class_list":["post-246905","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-entertainment"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/246905","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=246905"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/246905\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=246905"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=246905"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=246905"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}