{"id":246421,"date":"2026-11-03T02:34:14","date_gmt":"2026-11-03T08:34:14","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/11\/enhancing-the-cells-natural-recycling-center-improves-alzheimers-features-in-animal-models"},"modified":"2026-11-03T02:34:14","modified_gmt":"2026-11-03T08:34:14","slug":"enhancing-the-cells-natural-recycling-center-improves-alzheimers-features-in-animal-models","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/11\/enhancing-the-cells-natural-recycling-center-improves-alzheimers-features-in-animal-models","title":{"rendered":"Enhancing the cell\u2019s natural recycling center improves Alzheimer\u2019s features in animal models"},"content":{"rendered":"\n<p>A defining feature of Alzheimer\u2019s disease is the abnormal, sustained accumulation of protein aggregates such as tau inside brain cells, which disrupts the cells\u2019 normal functions. As time passes, brain cells stop working and die, leading to a gradual decline in memory and thinking skills and other symptoms of this condition.<\/p>\n<p>One goal of researchers is to find ways to reduce or stop the accumulation of tau and other related proteins to slow down or prevent disease progression.<\/p>\n<p>At Baylor College of Medicine and the Jan and Dan Duncan Neurological Research Institute (Duncan NRI) at Texas Children\u2019s Hospital, a team of researchers has just taken a step in that direction. They have discovered that reducing the levels of a protein called Slingshot-1 has the unanticipated effect of improving Alzheimer\u2019s features in animal models and human cells in the lab.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A defining feature of Alzheimer\u2019s disease is the abnormal, sustained accumulation of protein aggregates such as tau inside brain cells, which disrupts the cells\u2019 normal functions. As time passes, brain cells stop working and die, leading to a gradual decline in memory and thinking skills and other symptoms of this condition. One goal of researchers [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,47],"tags":[],"class_list":["post-246421","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/246421","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=246421"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/246421\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=246421"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=246421"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=246421"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}