{"id":246386,"date":"2026-11-03T00:41:00","date_gmt":"2026-11-03T06:41:00","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/11\/a-new-way-to-replace-carbon-with-nitrogen-atoms-could-lead-to-better-medicines"},"modified":"2026-11-03T00:41:00","modified_gmt":"2026-11-03T06:41:00","slug":"a-new-way-to-replace-carbon-with-nitrogen-atoms-could-lead-to-better-medicines","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/11\/a-new-way-to-replace-carbon-with-nitrogen-atoms-could-lead-to-better-medicines","title":{"rendered":"A new way to replace carbon with nitrogen atoms could lead to better medicines"},"content":{"rendered":"\n<p>When drugmakers want to improve on compounds they have already created, they can replace a carbon atom with a nitrogen atom. While effective, the techniques they use to perform this chemical swap, known as skeletal editing, have some downsides. For example, older approaches often require harsh chemicals or only work on specific types of molecules.<\/p>\n<p>That got researchers led by Mark D. Levin at the University of Chicago searching for a gentler and more versatile way to do it. Unlike older methods that fail when a specific chemical step goes wrong, their new technique turns that exact problem into a helpful tool.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>When drugmakers want to improve on compounds they have already created, they can replace a carbon atom with a nitrogen atom. While effective, the techniques they use to perform this chemical swap, known as skeletal editing, have some downsides. For example, older approaches often require harsh chemicals or only work on specific types of molecules. [\u2026]<\/p>\n","protected":false},"author":427,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,19],"tags":[],"class_list":["post-246386","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-chemistry"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/246386","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/427"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=246386"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/246386\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=246386"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=246386"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=246386"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}