{"id":246131,"date":"2026-10-29T06:16:23","date_gmt":"2026-10-29T11:16:23","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/10\/cancer-associated-adipocytes-in-the-tumor-microenvironment"},"modified":"2026-10-29T06:16:23","modified_gmt":"2026-10-29T11:16:23","slug":"cancer-associated-adipocytes-in-the-tumor-microenvironment","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/10\/cancer-associated-adipocytes-in-the-tumor-microenvironment","title":{"rendered":"Cancer-Associated Adipocytes in the Tumor Microenvironment"},"content":{"rendered":"\n<p>These stimuli suppress adipogenic markers while activating pathways associated with inflammation, fibrosis, and <a href=\"https:\/\/cancerbiologyresearch.com\/extracellular-matrix-ecm-cell-biology\/\" type=\"link\" id=\"https:\/\/cancerbiologyresearch.com\/extracellular-matrix-ecm-cell-biology\/\" target=\"_blank\" rel=\"noreferrer noopener\">extracellular matrix<\/a> remodeling. As a result, CAAs acquire fibroblast-like features and contribute actively to <a href=\"https:\/\/cancerbiologyresearch.com\/stages-of-carcinogenesis-explained-simply\/\" type=\"link\" id=\"https:\/\/cancerbiologyresearch.com\/stages-of-carcinogenesis-explained-simply\/\" target=\"_blank\" rel=\"noreferrer noopener\">tumor progression<\/a>.<\/p>\n<p>CAAs are most commonly found at the invasive front of tumors, where cancer cells interact directly with surrounding adipose tissue. This strategic localization allows CAAs to:<\/p>\n","protected":false},"excerpt":{"rendered":"<p>These stimuli suppress adipogenic markers while activating pathways associated with inflammation, fibrosis, and extracellular matrix remodeling. As a result, CAAs acquire fibroblast-like features and contribute actively to tumor progression. CAAs are most commonly found at the invasive front of tumors, where cancer cells interact directly with surrounding adipose tissue. This strategic localization allows CAAs to:<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-246131","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/246131","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=246131"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/246131\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=246131"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=246131"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=246131"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}