{"id":245921,"date":"2026-10-25T05:06:16","date_gmt":"2026-10-25T10:06:16","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/10\/an-extremely-old-giant-tortoise-named-jonathan-may-hold-the-secret-to-a-long-healthy-life"},"modified":"2026-10-25T05:06:16","modified_gmt":"2026-10-25T10:06:16","slug":"an-extremely-old-giant-tortoise-named-jonathan-may-hold-the-secret-to-a-long-healthy-life","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/10\/an-extremely-old-giant-tortoise-named-jonathan-may-hold-the-secret-to-a-long-healthy-life","title":{"rendered":"An extremely old giant tortoise named Jonathan may hold the secret to a long, healthy life"},"content":{"rendered":"\n<p>An international collaboration led by a neurologist and experts in advanced genomics at Vanderbilt Health has coaxed one of the secrets of extreme longevity from a 194-year-old giant tortoise named Jonathan.<\/p>\n<p>Jonathan\u2019s secret involves entropy, the tendency of biological systems to become disordered over time.<\/p>\n<p>One of the hallmarks of aging is mitochondrial dysfunction. It results from increasing entropy, or disorder, in \u201cpromoters,\u201d the genetic on-and-off switches that regulate the efficiency of mitochondria, the energy-producing organelles in most animal cells. A reliable supply of cellular energy is essential for many biological processes.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>An international collaboration led by a neurologist and experts in advanced genomics at Vanderbilt Health has coaxed one of the secrets of extreme longevity from a 194-year-old giant tortoise named Jonathan. Jonathan\u2019s secret involves entropy, the tendency of biological systems to become disordered over time. One of the hallmarks of aging is mitochondrial dysfunction. It [\u2026]<\/p>\n","protected":false},"author":707,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412,269],"tags":[],"class_list":["post-245921","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics","category-life-extension"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/245921","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/707"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=245921"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/245921\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=245921"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=245921"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=245921"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}