{"id":245735,"date":"2026-10-21T02:15:04","date_gmt":"2026-10-21T07:15:04","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/10\/smart-bomb-combination-attacks-triple-negative-breast-cancer-in-preclinical-study"},"modified":"2026-10-21T02:15:04","modified_gmt":"2026-10-21T07:15:04","slug":"smart-bomb-combination-attacks-triple-negative-breast-cancer-in-preclinical-study","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/10\/smart-bomb-combination-attacks-triple-negative-breast-cancer-in-preclinical-study","title":{"rendered":"\u2018Smart bomb\u2019 combination attacks triple-negative breast cancer in preclinical study"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/smart-bomb-combination-attacks-triple-negative-breast-cancer-in-preclinical-study.jpg\"><\/a><\/p>\n<p>A new preclinical study suggests that attacking triple-negative breast cancer (TNBC) in two ways at once can kill cancer cells, slow tumor growth and limit the cancer\u2019s spread. Researchers at The Ohio State University Comprehensive Cancer Center\u2014Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC\u2014James) developed the approach. The findings could help guide new treatments for this hard-to-treat form of breast cancer.<\/p>\n<p>\u201cThis study points to a possible new way to fight TNBC by pairing a targeted \u2018smart bomb\u2019 drug with a treatment that shuts down the cancer cells\u2019 energy factories,\u201d said Xiaoguang \u201cMargaret\u201d Liu, Ph.D., the study\u2019s corresponding author and a member of the OSUCCC\u2014James Translational Therapeutics Program. Liu also is a professor in Ohio State\u2019s College of Engineering. \u201cThese results are an early step. If the approach continues to work in laboratory studies and clinical trials, it could lead to a more effective treatment with fewer side effects than current options.\u201d<\/p>\n<p>The findings were <a href=\"https:\/\/www.cell.com\/cell-reports-medicine\/fulltext\/S2666-3791(26)00351-4\" target=\"_blank\">published<\/a> Aug. 18, 2026, in <i>Cell Reports Medicine<\/i>. The study helps scientists better understand how triple-negative breast cancer may survive treatment. It suggests the cancer may be more vulnerable when one treatment delivers a drug directly to cancer cells and another cuts off their energy supply.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A new preclinical study suggests that attacking triple-negative breast cancer (TNBC) in two ways at once can kill cancer cells, slow tumor growth and limit the cancer\u2019s spread. Researchers at The Ohio State University Comprehensive Cancer Center\u2014Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC\u2014James) developed the approach. The findings could help [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-245735","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/245735","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=245735"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/245735\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=245735"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=245735"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=245735"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}