{"id":245705,"date":"2026-10-20T21:11:48","date_gmt":"2026-10-21T02:11:48","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/10\/a-microbiome-bile-acid-axis-mediates-protection-from-chronic-liver-disease-in-females"},"modified":"2026-10-20T21:11:48","modified_gmt":"2026-10-21T02:11:48","slug":"a-microbiome-bile-acid-axis-mediates-protection-from-chronic-liver-disease-in-females","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/10\/a-microbiome-bile-acid-axis-mediates-protection-from-chronic-liver-disease-in-females","title":{"rendered":"A microbiome-bile acid axis mediates protection from chronic liver disease in females"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/a-microbiome-bile-acid-axis-mediates-protection-from-chronic-liver-disease-in-females2.jpg\"><\/a><\/p>\n<p>IsoUDCA, a female-enriched bile acid produced by a gut bacterial consortium favored by estrogen, promotes hepatic cholesterol handling and bile acid metabolism through SREBP2-<i>STARD4<\/i>-CYP7B1 signaling, thereby alleviating chronic liver injury.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>IsoUDCA, a female-enriched bile acid produced by a gut bacterial consortium favored by estrogen, promotes hepatic cholesterol handling and bile acid metabolism through SREBP2-STARD4-CYP7B1 signaling, thereby alleviating chronic liver injury.<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-245705","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/245705","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=245705"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/245705\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=245705"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=245705"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=245705"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}