{"id":245674,"date":"2026-10-19T23:17:26","date_gmt":"2026-10-20T04:17:26","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/10\/bespoke-library-docking-for-5-ht2a-receptor-agonists-with-antidepressant-activity"},"modified":"2026-10-19T23:17:26","modified_gmt":"2026-10-20T04:17:26","slug":"bespoke-library-docking-for-5-ht2a-receptor-agonists-with-antidepressant-activity","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/10\/bespoke-library-docking-for-5-ht2a-receptor-agonists-with-antidepressant-activity","title":{"rendered":"Bespoke library docking for 5-HT2A receptor agonists with antidepressant activity"},"content":{"rendered":"<p style=\"padding-right: 20px\"><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/bespoke-library-docking-for-5-ht2a-receptor-agonists-with-antidepressant-activity.jpg\"><\/a><\/p>\n<p>This new compound can lead to better treatment of depression using essentially a non hallucinogenic version of lsd. This lead to essentially many discoveries including the 5-HT2A receptor in the human brain which can help make the new compounds more accurate for the new compound. This would help with more effective treatment of treatment resistant depression.<\/p>\n<hr>\n<p>New agonists of the serotonin 5-HT2A receptor (5-HT2AR) confer high brain permeability and antidepressant activity and\u2014in contrast to classic 5-HT2AR agonists\u2014lack psychedelic activity.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>This new compound can lead to better treatment of depression using essentially a non hallucinogenic version of lsd. This lead to essentially many discoveries including the 5-HT2A receptor in the human brain which can help make the new compounds more accurate for the new compound. This would help with more effective treatment of treatment resistant [\u2026]<\/p>\n","protected":false},"author":513,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[47],"tags":[],"class_list":["post-245674","post","type-post","status-publish","format-standard","hentry","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/245674","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/513"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=245674"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/245674\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=245674"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=245674"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=245674"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}