{"id":245242,"date":"2026-10-11T17:09:27","date_gmt":"2026-10-11T22:09:27","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/10\/non-invasive-nanoparticle-barcoding-in-nonhuman-primates"},"modified":"2026-10-11T17:09:27","modified_gmt":"2026-10-11T22:09:27","slug":"non-invasive-nanoparticle-barcoding-in-nonhuman-primates","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/10\/non-invasive-nanoparticle-barcoding-in-nonhuman-primates","title":{"rendered":"Non-invasive nanoparticle barcoding in nonhuman primates"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/non-invasive-nanoparticle-barcoding-in-nonhuman-primates.jpg\"><\/a><\/p>\n<p><i>et al.<\/i> developed a clever DNA barcode system to measure pooled lipid nanoparticle (LNP) delivery in nonhuman primates by taking small samples of serum. This allows high-throughput NHP screening of the efficacy of LNP formulations without killing monkeys. However, a limitation of the technique is that the readout does not encode which tissues the LNPs reach. Nonetheless, I expect this method will accelerate LNP discovery while minimizing harm to NHP animals.<\/p>\n<hr>\n<p>Simultaneous delivery of several lipid nanoparticles is quantified using snapCodes in a single nonhuman primate.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>et al. developed a clever DNA barcode system to measure pooled lipid nanoparticle (LNP) delivery in nonhuman primates by taking small samples of serum. This allows high-throughput NHP screening of the efficacy of LNP formulations without killing monkeys. However, a limitation of the technique is that the readout does not encode which tissues the LNPs [\u2026]<\/p>\n","protected":false},"author":636,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,4],"tags":[],"class_list":["post-245242","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-nanotechnology"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/245242","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/636"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=245242"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/245242\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=245242"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=245242"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=245242"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}