{"id":245146,"date":"2026-10-09T21:18:43","date_gmt":"2026-10-10T02:18:43","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/10\/multimodal-profiling-uncovers-an-aging-associated-ets1-myo1b-vascular-niche-responsive-to-ipragliflozin"},"modified":"2026-10-09T21:18:43","modified_gmt":"2026-10-10T02:18:43","slug":"multimodal-profiling-uncovers-an-aging-associated-ets1-myo1b-vascular-niche-responsive-to-ipragliflozin","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/10\/multimodal-profiling-uncovers-an-aging-associated-ets1-myo1b-vascular-niche-responsive-to-ipragliflozin","title":{"rendered":"Multimodal profiling uncovers an aging-associated ETS1-MYO1B vascular niche responsive to ipragliflozin"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/multimodal-profiling-uncovers-an-aging-associated-ets1-myo1b-vascular-niche-responsive-to-ipragliflozin.webp\"><\/a><\/p>\n<p>:<\/p>\n<p>Tissue aging involves complex changes in vascular, immune, and stromal compartments that collectively reshape the local tissue ecosystem and may contribute to age-related diseases, including cancer, fibrotic diseases, and cardiovascular disease. However, it remains unclear whether reproducible, cell-specific vascular niche states emerge during aging and whether these states can be therapeutically targeted.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>: Tissue aging involves complex changes in vascular, immune, and stromal compartments that collectively reshape the local tissue ecosystem and may contribute to age-related diseases, including cancer, fibrotic diseases, and cardiovascular disease. However, it remains unclear whether reproducible, cell-specific vascular niche states emerge during aging and whether these states can be therapeutically targeted.<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,269],"tags":[],"class_list":["post-245146","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-life-extension"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/245146","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=245146"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/245146\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=245146"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=245146"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=245146"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}