{"id":244993,"date":"2026-10-06T22:11:48","date_gmt":"2026-10-07T03:11:48","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/10\/blocking-a-nerve-protein-could-interrupt-chronic-pain-rather-than-simply-mask-it"},"modified":"2026-10-06T22:11:48","modified_gmt":"2026-10-07T03:11:48","slug":"blocking-a-nerve-protein-could-interrupt-chronic-pain-rather-than-simply-mask-it","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/10\/blocking-a-nerve-protein-could-interrupt-chronic-pain-rather-than-simply-mask-it","title":{"rendered":"Blocking a nerve protein could interrupt chronic pain rather than simply mask it"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/blocking-a-nerve-protein-could-interrupt-chronic-pain-rather-than-simply-mask-it2.jpg\"><\/a><\/p>\n<p>Chronic pain can continue long after an initial injury. When a nerve outside the brain and spinal cord (a peripheral nerve) is damaged and does not heal properly, it keeps sending constant pain signals. Over time, this nonstop bombardment of pain signals changes how your spinal cord and brain process information as sensory and emotion-associated circuits become hyperreactive, turning up the volume on pain.<\/p>\n<p>Current pain treatments do not work well for everyone and can cause significant side effects. Painkillers like morphine just hide the pain, but researchers at Boston University Chobanian &amp; Avedisian School of Medicine have identified the underlying problem.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Chronic pain can continue long after an initial injury. When a nerve outside the brain and spinal cord (a peripheral nerve) is damaged and does not heal properly, it keeps sending constant pain signals. Over time, this nonstop bombardment of pain signals changes how your spinal cord and brain process information as sensory and emotion-associated [\u2026]<\/p>\n","protected":false},"author":427,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,47],"tags":[],"class_list":["post-244993","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/244993","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/427"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=244993"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/244993\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=244993"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=244993"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=244993"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}