{"id":244759,"date":"2026-10-01T11:13:32","date_gmt":"2026-10-01T16:13:32","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/10\/dopamine-depletion-in-mice-reveals-potential-adhd-treatment-target"},"modified":"2026-10-01T11:13:32","modified_gmt":"2026-10-01T16:13:32","slug":"dopamine-depletion-in-mice-reveals-potential-adhd-treatment-target","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/10\/dopamine-depletion-in-mice-reveals-potential-adhd-treatment-target","title":{"rendered":"Dopamine Depletion in Mice Reveals Potential ADHD Treatment Target"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/dopamine-depletion-in-mice-reveals-potential-adhd-treatment-target.jpg\"><\/a><\/p>\n<p>Researchers deleted NSF from D2 receptor-expressing cells in mice, causing striatal cell loss, a ~90% dopamine decline, and an increase in ADHD-like behaviors. Activating D2 receptors alongside methylphenidate reduced hyperactivity and impulsivity.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Researchers deleted NSF from D2 receptor-expressing cells in mice, causing striatal cell loss, a ~90% dopamine decline, and an increase in ADHD-like behaviors. Activating D2 receptors alongside methylphenidate reduced hyperactivity and impulsivity.<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[47],"tags":[],"class_list":["post-244759","post","type-post","status-publish","format-standard","hentry","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/244759","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=244759"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/244759\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=244759"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=244759"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=244759"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}