{"id":244332,"date":"2026-09-21T21:38:14","date_gmt":"2026-09-22T02:38:14","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/09\/new-ligand-design-balances-radical-generation-and-catalyst-regeneration-for-challenging-chemical-reactions"},"modified":"2026-09-21T21:38:14","modified_gmt":"2026-09-22T02:38:14","slug":"new-ligand-design-balances-radical-generation-and-catalyst-regeneration-for-challenging-chemical-reactions","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/09\/new-ligand-design-balances-radical-generation-and-catalyst-regeneration-for-challenging-chemical-reactions","title":{"rendered":"New ligand design balances radical generation and catalyst regeneration for challenging chemical reactions"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/new-ligand-design-balances-radical-generation-and-catalyst-regeneration-for-challenging-chemical-reactions.jpg\"><\/a><\/p>\n<p>Radicals, atoms or molecules that readily react with other substances to form new bonds, are useful tools for building complex substances such as pharmaceuticals. But even when a radical is generated efficiently, the reaction cannot continue unless the catalyst returns to its original state.<\/p>\n<p>A KAIST research team has developed a new strategy that balances radical generation and catalyst regeneration, broadening the possibility of using substrates that are difficult to activate to synthesize complex molecules needed for pharmaceuticals and other applications.<\/p>\n<p>The research team led by Professor Sarah Yunmi Lee of the Department of Chemistry developed a method that uses a ligand, a molecule that attaches to a metal catalyst and controls its properties, to effectively regulate the process by which a copper catalyst generates a radical and then returns to its original state.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Radicals, atoms or molecules that readily react with other substances to form new bonds, are useful tools for building complex substances such as pharmaceuticals. But even when a radical is generated efficiently, the reaction cannot continue unless the catalyst returns to its original state. A KAIST research team has developed a new strategy that balances [\u2026]<\/p>\n","protected":false},"author":427,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[19,48],"tags":[],"class_list":["post-244332","post","type-post","status-publish","format-standard","hentry","category-chemistry","category-particle-physics"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/244332","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/427"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=244332"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/244332\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=244332"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=244332"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=244332"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}