{"id":244223,"date":"2026-09-18T21:03:11","date_gmt":"2026-09-19T02:03:11","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/09\/clearing-damaged-mitochondria-to-fight-skin-photoaging"},"modified":"2026-09-18T21:03:11","modified_gmt":"2026-09-19T02:03:11","slug":"clearing-damaged-mitochondria-to-fight-skin-photoaging","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/09\/clearing-damaged-mitochondria-to-fight-skin-photoaging","title":{"rendered":"Clearing Damaged Mitochondria to Fight Skin Photoaging"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/clearing-damaged-mitochondria-to-fight-skin-photoaging.jpg\"><\/a><\/p>\n<p>Researchers publishing in <i>Aging Cell<\/i> have found that a cocktail of molecules released by human umbilical cord mesenchymal stem cells (hUC-MSCs) can mitigate sun-induced skin aging (photoaging) in mice by restoring their cells\u2019 ability to get rid of their own damaged mitochondria (mitophagy).<\/p>\n<p><b><b>Wrinkles are only a small part of the problem<\/b><\/b><\/p>\n<p>Chronic exposure to ultraviolet light is the main driver of photoaging, which is characterized by the accumulation of senescent cells in the skin along with the depletion of DNA-protecting lamins [1]. It causes skin to become thickened, wrinkled, and rough while accumulating visible veins [2]. This damage is more than cosmetic; photoaging can lead to precancerous lesions along with cancer itself [3]. Retinoids and other antioxidants have been found to have some effects but cannot completely reverse this damage [4], and laser-based treatments may be expensive and painful while causing other symptoms [5].<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Researchers publishing in Aging Cell have found that a cocktail of molecules released by human umbilical cord mesenchymal stem cells (hUC-MSCs) can mitigate sun-induced skin aging (photoaging) in mice by restoring their cells\u2019 ability to get rid of their own damaged mitochondria (mitophagy). Wrinkles are only a small part of the problem Chronic exposure to [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,269],"tags":[],"class_list":["post-244223","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-life-extension"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/244223","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=244223"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/244223\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=244223"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=244223"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=244223"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}