{"id":244122,"date":"2026-09-17T01:04:06","date_gmt":"2026-09-17T06:04:06","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/09\/copper-ion-induced-myh9-polymerization-executes-cuproptosis"},"modified":"2026-09-17T01:04:06","modified_gmt":"2026-09-17T06:04:06","slug":"copper-ion-induced-myh9-polymerization-executes-cuproptosis","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/09\/copper-ion-induced-myh9-polymerization-executes-cuproptosis","title":{"rendered":"Copper ion-induced MYH9 polymerization executes cuproptosis"},"content":{"rendered":"<p style=\"padding-right: 20px\"><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/copper-ion-induced-myh9-polymerization-executes-cuproptosis2.jpg\"><\/a><\/p>\n<p>Copper binding drives MYH9 polymerization, triggering cytoskeletal collapse and cuproptosis. HThPA releases intracellular copper through glutathione depletion, exposing a therapeutic vulnerability in drug-resistant tumors.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Copper binding drives MYH9 polymerization, triggering cytoskeletal collapse and cuproptosis. HThPA releases intracellular copper through glutathione depletion, exposing a therapeutic vulnerability in drug-resistant tumors.<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-244122","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/244122","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=244122"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/244122\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=244122"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=244122"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=244122"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}