{"id":243475,"date":"2026-09-01T09:15:07","date_gmt":"2026-09-01T14:15:07","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/09\/impaired-behavioral-inhibition-in-fmr1-ko-mice-is-linked-to-disrupted-visual-cortex-theta-oscillations"},"modified":"2026-09-01T09:15:07","modified_gmt":"2026-09-01T14:15:07","slug":"impaired-behavioral-inhibition-in-fmr1-ko-mice-is-linked-to-disrupted-visual-cortex-theta-oscillations","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/09\/impaired-behavioral-inhibition-in-fmr1-ko-mice-is-linked-to-disrupted-visual-cortex-theta-oscillations","title":{"rendered":"Impaired behavioral inhibition in Fmr1 KO mice is linked to disrupted visual cortex theta oscillations"},"content":{"rendered":"<p style=\"padding-right: 20px\"><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/impaired-behavioral-inhibition-in-fmr1-ko-mice-is-linked-to-disrupted-visual-cortex-theta-oscillations2.jpg\"><\/a><\/p>\n<p>Zimmerman et al. show loss of behavioral inhibition correlated with attenuated theta activity in the primary visual cortex, hippocampus, and deficient top-down control from the prefrontal cortex in the Fmr1 KO mice. These findings shed light on circuit-level impairments underlying behavioral deficits in Fragile X syndrome for potential therapeutic interventions.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Zimmerman et al. show loss of behavioral inhibition correlated with attenuated theta activity in the primary visual cortex, hippocampus, and deficient top-down control from the prefrontal cortex in the Fmr1 KO mice. These findings shed light on circuit-level impairments underlying behavioral deficits in Fragile X syndrome for potential therapeutic interventions.<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[47],"tags":[],"class_list":["post-243475","post","type-post","status-publish","format-standard","hentry","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/243475","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=243475"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/243475\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=243475"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=243475"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=243475"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}