{"id":243460,"date":"2026-09-01T05:19:00","date_gmt":"2026-09-01T10:19:00","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/09\/one-pot-crispr-platform-delivers-lab-like-sensitivity-in-30-minutes-for-at-home-testing"},"modified":"2026-09-01T05:19:00","modified_gmt":"2026-09-01T10:19:00","slug":"one-pot-crispr-platform-delivers-lab-like-sensitivity-in-30-minutes-for-at-home-testing","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/09\/one-pot-crispr-platform-delivers-lab-like-sensitivity-in-30-minutes-for-at-home-testing","title":{"rendered":"\u2018One-pot\u2019 CRISPR platform delivers lab-like sensitivity in 30 minutes for at-home testing"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/one-pot-crispr-platform-delivers-lab-like-sensitivity-in-30-minutes-for-at-home-testing2.jpg\"><\/a><\/p>\n<p>A research team from The Hong Kong University of Science and Technology (HKUST) has developed an innovative \u201cone-pot\u201d testing platform, known as TEMPO, that could transform highly sensitive nucleic acid testing from a laboratory-based procedure into a simple, single-step test that can be performed at home. With a single reaction tube, users can obtain results comparable to those of professional laboratory tests in as little as 30 minutes. The breakthrough has the potential to bridge the technological gap between existing rapid tests and laboratory-based nucleic acid diagnostics, offering a more convenient solution for future infectious disease surveillance and genetic screening.<\/p>\n<p>TEMPO, short for \u201cThermodynamically Encoded Molecular Programming for One-Pot Diagnostics,\u201d was jointly developed by a research team led by Hsing I-Ming, a professor in the Department of Chemical and Biological Engineering at HKUST, and researchers from The Chinese University of Hong Kong. The platform has already demonstrated applications in the detection of a range of viral infections, including influenza, COVID-19 and HIV, while also opening new possibilities for the rapid screening of hereditary diseases.<\/p>\n<p>The study, titled \u201cThermodynamically programmed one-pot CRISPR platform for point-of-care SNP genotyping,\u201d is <a href=\"https:\/\/www.nature.com\/articles\/s41467-026-75358-1\" target=\"_blank\">published<\/a> in the journal <i>Nature Communications.<\/i><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A research team from The Hong Kong University of Science and Technology (HKUST) has developed an innovative \u201cone-pot\u201d testing platform, known as TEMPO, that could transform highly sensitive nucleic acid testing from a laboratory-based procedure into a simple, single-step test that can be performed at home. With a single reaction tube, users can obtain results [\u2026]<\/p>\n","protected":false},"author":427,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1902,11,19,412],"tags":[],"class_list":["post-243460","post","type-post","status-publish","format-standard","hentry","category-bioengineering","category-biotech-medical","category-chemistry","category-genetics"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/243460","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/427"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=243460"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/243460\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=243460"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=243460"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=243460"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}