{"id":243204,"date":"2026-08-26T01:22:35","date_gmt":"2026-08-26T06:22:35","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/08\/stress-gene-stuck-on-in-the-brains-of-people-with-schizophrenia-study-finds"},"modified":"2026-08-26T01:22:35","modified_gmt":"2026-08-26T06:22:35","slug":"stress-gene-stuck-on-in-the-brains-of-people-with-schizophrenia-study-finds","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/08\/stress-gene-stuck-on-in-the-brains-of-people-with-schizophrenia-study-finds","title":{"rendered":"Stress gene \u2018stuck on\u2019 in the brains of people with schizophrenia, study finds"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/stress-gene-stuck-on-in-the-brains-of-people-with-schizophrenia-study-finds2.jpg\"><\/a><\/p>\n<p>Experts at the University of Sydney have found that a gene involved in regulating the body\u2019s response to stress switches on more easily in the brains of people who live with schizophrenia.<\/p>\n<p>The study, published in the <i>American Journal of Psychiatry<\/i> and carried out in collaboration with researchers at the Max Planck Institute of Psychiatry, looked at the FKBP5 gene and the corresponding FKBP51 protein, which help regulate how strongly the body responds to stress hormones such as cortisol.<\/p>\n<p>Using donated brain tissue, the researchers found that for people with schizophrenia, the chemical tags that normally keep the FKBP5 gene in check had been stripped away. This change was linked to higher activity of the FKBP5 gene, opening up the possibility of developing new treatments that target it.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Experts at the University of Sydney have found that a gene involved in regulating the body\u2019s response to stress switches on more easily in the brains of people who live with schizophrenia. The study, published in the American Journal of Psychiatry and carried out in collaboration with researchers at the Max Planck Institute of Psychiatry, [\u2026]<\/p>\n","protected":false},"author":427,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[19,47],"tags":[],"class_list":["post-243204","post","type-post","status-publish","format-standard","hentry","category-chemistry","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/243204","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/427"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=243204"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/243204\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=243204"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=243204"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=243204"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}