{"id":243108,"date":"2026-08-23T21:05:33","date_gmt":"2026-08-24T02:05:33","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/08\/study-suggests-40hz-sensory-stimulation-may-benefit-some-alzheimers-patients-for-years"},"modified":"2026-08-23T21:05:33","modified_gmt":"2026-08-24T02:05:33","slug":"study-suggests-40hz-sensory-stimulation-may-benefit-some-alzheimers-patients-for-years","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/08\/study-suggests-40hz-sensory-stimulation-may-benefit-some-alzheimers-patients-for-years","title":{"rendered":"Study suggests 40Hz sensory stimulation may benefit some Alzheimer\u2019s patients for years"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/study-suggests-40hz-sensory-stimulation-may-benefit-some-alzheimers-patients-for-years.jpg\"><\/a><\/p>\n<p>A new research paper documents the outcomes of five volunteers who continued to receive 40Hz light and sound stimulation for around two years after participating in an MIT <a href=\"https:\/\/live-picower-170706.pantheonsite.io\/node\/1034\">early-stage clinical study<\/a> of the potential Alzheimer\u2019s disease (AD) therapy. The results show that for the three participants with late-onset Alzheimer\u2019s disease, several measures of cognition remained significantly higher than comparable Alzheimer\u2019s patients in national databases. Moreover, in the two late-onset volunteers who donated plasma samples, levels of Alzheimer\u2019s biomarker tau proteins were significantly decreased.<\/p>\n<p>The three volunteers who experienced these benefits were all female. The two other participants, each of whom were males with early-onset forms of the disease, did not exhibit significant benefits after two years. The dataset, while small, represents the longest-term test so far of the safe, noninvasive treatment method (called GENUS, for gamma entrainment using sensory stimuli), which is also being evaluated in a nationwide clinical trial run by MIT-spinoff company Cognito Therapeutics.<\/p>\n<p>\u201cThis pilot study assessed the long-term effects of daily 40Hz multimodal GENUS in patients with mild AD,\u201d the authors wrote in an open-access <a href=\"https:\/\/alz-journals.onlinelibrary.wiley.com\/doi\/10.1002\/alz.70792\">paper in <em>Alzheimer\u2019s &amp; Dementia: The<\/em> <em>Journal of the Alzheimer\u2019s Association<\/em><\/a>. \u201cWe found that daily 40Hz audiovisual stimulation over 2 years is safe, feasible, and may slow cognitive decline and biomarker progression, especially in late-onset AD patients.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A new research paper documents the outcomes of five volunteers who continued to receive 40Hz light and sound stimulation for around two years after participating in an MIT early-stage clinical study of the potential Alzheimer\u2019s disease (AD) therapy. The results show that for the three participants with late-onset Alzheimer\u2019s disease, several measures of cognition remained [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,47],"tags":[],"class_list":["post-243108","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/243108","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=243108"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/243108\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=243108"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=243108"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=243108"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}