{"id":242361,"date":"2026-08-07T13:03:37","date_gmt":"2026-08-07T18:03:37","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/08\/drug-temporarily-reverses-autism-like-brain-changes-in-adult-mice-within-hours"},"modified":"2026-08-07T13:03:37","modified_gmt":"2026-08-07T18:03:37","slug":"drug-temporarily-reverses-autism-like-brain-changes-in-adult-mice-within-hours","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/08\/drug-temporarily-reverses-autism-like-brain-changes-in-adult-mice-within-hours","title":{"rendered":"Drug temporarily reverses autism-like brain changes in adult mice within hours"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/drug-temporarily-reverses-autism-like-brain-changes-in-adult-mice-within-hours.jpg\"><\/a><\/p>\n<p>A new mouse study led by UCLA Health suggests that inflammation during pregnancy can trigger autism-like changes in offspring, but those brain and behavioral effects may be rapidly, though temporarily, reversible in adulthood with a single dose of the immunosuppressive drug rapamycin.<\/p>\n<p>Even mild inflammation during midpregnancy has been shown to result in autism-like symptoms in offspring, abnormal brain growth, seizures and heightened sensitivity to everyday sensory input that persist into adulthood.<\/p>\n<p>In the study published in the journal Nature Communications, UCLA researchers found that a single dose of rapamycin significantly improved brain signaling and behavioral symptoms in these offspring within about two hours, too short a time to correct underlying physical brain changes caused by maternal inflammation.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A new mouse study led by UCLA Health suggests that inflammation during pregnancy can trigger autism-like changes in offspring, but those brain and behavioral effects may be rapidly, though temporarily, reversible in adulthood with a single dose of the immunosuppressive drug rapamycin. Even mild inflammation during midpregnancy has been shown to result in autism-like symptoms [\u2026]<\/p>\n","protected":false},"author":707,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,1495,47],"tags":[],"class_list":["post-242361","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-health","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/242361","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/707"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=242361"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/242361\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=242361"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=242361"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=242361"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}