{"id":242090,"date":"2026-08-03T01:13:51","date_gmt":"2026-08-03T06:13:51","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/08\/longitudinal-plasma-proteomics-predict-phenoconversion-to-clinically-manifest-als"},"modified":"2026-08-03T01:13:51","modified_gmt":"2026-08-03T06:13:51","slug":"longitudinal-plasma-proteomics-predict-phenoconversion-to-clinically-manifest-als","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/08\/longitudinal-plasma-proteomics-predict-phenoconversion-to-clinically-manifest-als","title":{"rendered":"Longitudinal plasma proteomics predict phenoconversion to clinically manifest ALS"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/longitudinal-plasma-proteomics-predict-phenoconversion-to-clinically-manifest-als.jpg\"><\/a><\/p>\n<p>Longitudinal proteomic analysis of plasma from unaffected carriers of ALS-associated pathogenic variants revealed early protein changes before ALS symptoms and enabled mapping of their trajectories as well as prediction of the timing of phenoconversion<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Longitudinal proteomic analysis of plasma from unaffected carriers of ALS-associated pathogenic variants revealed early protein changes before ALS symptoms and enabled mapping of their trajectories as well as prediction of the timing of phenoconversion<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-242090","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/242090","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=242090"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/242090\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=242090"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=242090"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=242090"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}