{"id":241871,"date":"2026-07-30T20:04:49","date_gmt":"2026-07-31T01:04:49","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/07\/brain-dramatically-remodels-its-cellular-composition-starting-in-midlife"},"modified":"2026-07-30T20:04:49","modified_gmt":"2026-07-31T01:04:49","slug":"brain-dramatically-remodels-its-cellular-composition-starting-in-midlife","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/07\/brain-dramatically-remodels-its-cellular-composition-starting-in-midlife","title":{"rendered":"Brain Dramatically Remodels Its Cellular Composition, Starting in Midlife"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/brain-dramatically-remodels-its-cellular-composition-starting-in-midlife.jpg\"><\/a><\/p>\n<p>The aging human brain is fascinating, because in some ways, it <a href=\"https:\/\/www.sciencealert.com\/aging-isn-t-all-bad-some-key-mental-abilities-improve-as-we-get-older\">improves with age<\/a> \u2013 but we generally hear more about how it declines. That\u2019s understandable!<\/p>\n<p>After all, there are a host of neurodegenerative diseases that none of us want to end up with.<\/p>\n<p>Previous research has shown that some of the seemingly inevitable declines in brain health, often seen in 70-and 80-year old brains, <a href=\"https:\/\/doi.org\/10.1016\/j.tins.2024.02.001\">start in midlife<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The aging human brain is fascinating, because in some ways, it improves with age \u2013 but we generally hear more about how it declines. That\u2019s understandable! After all, there are a host of neurodegenerative diseases that none of us want to end up with. Previous research has shown that some of the seemingly inevitable declines [\u2026]<\/p>\n","protected":false},"author":692,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,269,47],"tags":[],"class_list":["post-241871","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-life-extension","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/241871","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/692"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=241871"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/241871\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=241871"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=241871"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=241871"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}