{"id":241761,"date":"2026-07-29T00:27:22","date_gmt":"2026-07-29T05:27:22","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/07\/human-tissue-model-tracks-glioblastoma-invasion-cell-by-cell"},"modified":"2026-07-29T00:27:22","modified_gmt":"2026-07-29T05:27:22","slug":"human-tissue-model-tracks-glioblastoma-invasion-cell-by-cell","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/07\/human-tissue-model-tracks-glioblastoma-invasion-cell-by-cell","title":{"rendered":"Human tissue model tracks glioblastoma invasion cell by cell"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/human-tissue-model-tracks-glioblastoma-invasion-cell-by-cell2.jpg\"><\/a><\/p>\n<p>Glioblastoma is a malignant brain tumor and is among the most aggressive cancers in humans. Despite multimodal therapy with surgery, radiation and chemotherapy, there is still no cure. A major reason is the tumor\u2019s invasive behavior: Glioblastoma cells migrate far beyond the visible tumor into healthy brain tissue. These infiltrating cells cannot be completely removed and seed tumor recurrence\u2014often within just a few months.<\/p>\n<p>\u201cTo understand why glioblastoma keeps coming back, we need to look closely at the tumor cells that remain hidden in the brain after surgery,\u201d says Dr. Matthias Schneider, deputy director of the Department of Neurosurgery at the UKB and head of the Brain Tumor Translational Research Group at the UKB and the University of Bonn. \u201cCore2Edge allows us to study these infiltrative tumor cells in a model based entirely on human tissue, closely mirroring what we see in patients.\u201d<\/p>\n<p>The study is <a href=\"https:\/\/www.nature.com\/articles\/s41596-026-01412-3\" target=\"_blank\">published<\/a> in the journal Nature Protocols.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Glioblastoma is a malignant brain tumor and is among the most aggressive cancers in humans. Despite multimodal therapy with surgery, radiation and chemotherapy, there is still no cure. A major reason is the tumor\u2019s invasive behavior: Glioblastoma cells migrate far beyond the visible tumor into healthy brain tissue. These infiltrating cells cannot be completely removed [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,47],"tags":[],"class_list":["post-241761","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/241761","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=241761"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/241761\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=241761"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=241761"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=241761"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}