{"id":241505,"date":"2026-07-24T16:11:27","date_gmt":"2026-07-24T21:11:27","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/07\/giving-antibodies-eyes-may-help-target-hidden-kras-mutations-in-cancer-cells"},"modified":"2026-07-24T16:11:27","modified_gmt":"2026-07-24T21:11:27","slug":"giving-antibodies-eyes-may-help-target-hidden-kras-mutations-in-cancer-cells","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/07\/giving-antibodies-eyes-may-help-target-hidden-kras-mutations-in-cancer-cells","title":{"rendered":"Giving antibodies \u2018eyes\u2019 may help target hidden KRAS mutations in cancer cells"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/giving-antibodies-eyes-may-help-target-hidden-kras-mutations-in-cancer-cells2.jpg\"><\/a><\/p>\n<p>Antibodies are like \u201cguided missiles\u201d that find and attack cancer cells, but cancer-causing mutations inside cells have remained a \u201cblind spot\u201d for treatment because antibodies cannot reach them. KAIST researchers have now succeeded in precisely targeting intracellular cancer mutations using a newly designed antibody created through computational methods.<\/p>\n<p>The work is <a href=\"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1525001626004776\" target=\"_blank\">published<\/a> in the journal Molecular Therapy.<\/p>\n<p>This achievement is expected to open a new path toward next-generation precision therapies for difficult-to-treat cancers, going beyond the limitations of conventional antibody treatments.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Antibodies are like \u201cguided missiles\u201d that find and attack cancer cells, but cancer-causing mutations inside cells have remained a \u201cblind spot\u201d for treatment because antibodies cannot reach them. KAIST researchers have now succeeded in precisely targeting intracellular cancer mutations using a newly designed antibody created through computational methods. The work is published in the journal [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,1523],"tags":[],"class_list":["post-241505","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-computing"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/241505","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=241505"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/241505\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=241505"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=241505"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=241505"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}