{"id":241297,"date":"2026-07-22T00:14:50","date_gmt":"2026-07-22T05:14:50","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/07\/high-speed-3d-imaging-reveals-how-seizures-move-through-the-brain"},"modified":"2026-07-22T00:14:50","modified_gmt":"2026-07-22T05:14:50","slug":"high-speed-3d-imaging-reveals-how-seizures-move-through-the-brain","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/07\/high-speed-3d-imaging-reveals-how-seizures-move-through-the-brain","title":{"rendered":"High-speed 3D imaging reveals how seizures move through the brain"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/high-speed-3d-imaging-reveals-how-seizures-move-through-the-brain.jpg\"><\/a><\/p>\n<p>Seizures can race through the brain in seconds, making them difficult to capture in detail. To overcome this challenge, researchers have developed a new high-resolution light-sheet imaging system that is fast enough to image seizure propagation in the brain of a larval zebrafish in 3D.<\/p>\n<p>\u201cWe developed a light-sheet microscope that allows rapid volumetric imaging with real-time correction of aberrations\u2014imperfections in the way a microscope forms an image,\u201d said research team leader Peter Kner from the University of Georgia. \u201cMost imaging of seizure events in zebrafish has only captured 2D images, but our system allows 3D high-resolution imaging over a larger volume than was previously possible.\u201d<\/p>\n<p>In their <a href=\"https:\/\/opg.optica.org\/abstract.cfm?URI=boe-17-8-4216\" target=\"_blank\">article<\/a> published in the journal <i>Biomedical Optics Express<\/i>, the researchers show that their new microscopy system can capture volumes up to 499 \u00d7 499 \u00d7 150 microns<sup>3<\/sup> at a rate of four volumes per second with near-diffraction-limited resolution. They used the system to observe how seizures spread through the nervous system in zebrafish larvae, which are commonly used in neuroscience research.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Seizures can race through the brain in seconds, making them difficult to capture in detail. To overcome this challenge, researchers have developed a new high-resolution light-sheet imaging system that is fast enough to image seizure propagation in the brain of a larval zebrafish in 3D. \u201cWe developed a light-sheet microscope that allows rapid volumetric imaging [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[47],"tags":[],"class_list":["post-241297","post","type-post","status-publish","format-standard","hentry","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/241297","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=241297"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/241297\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=241297"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=241297"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=241297"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}