{"id":240986,"date":"2026-07-16T00:48:45","date_gmt":"2026-07-16T05:48:45","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/07\/joint-trajectories-of-brain-atrophy-white-matter-hyperintensities-and-cognition-quantify-brain-maintenance"},"modified":"2026-07-16T00:48:45","modified_gmt":"2026-07-16T05:48:45","slug":"joint-trajectories-of-brain-atrophy-white-matter-hyperintensities-and-cognition-quantify-brain-maintenance","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/07\/joint-trajectories-of-brain-atrophy-white-matter-hyperintensities-and-cognition-quantify-brain-maintenance","title":{"rendered":"Joint trajectories of brain atrophy, white matter hyperintensities and cognition quantify brain maintenance"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/joint-trajectories-of-brain-atrophy-white-matter-hyperintensities-and-cognition-quantify-brain-maintenance2.jpg\"><\/a><\/p>\n<p>Joint longitudinal modelling of brain atrophy, white matter damage, and cognition in 543 older adults yielded a brain maintenance index. Poorer mental health, lower openness, and faster biological ageing predicted reduced maintenance.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Joint longitudinal modelling of brain atrophy, white matter damage, and cognition in 543 older adults yielded a brain maintenance index. Poorer mental health, lower openness, and faster biological ageing predicted reduced maintenance.<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3,269,47],"tags":[],"class_list":["post-240986","post","type-post","status-publish","format-standard","hentry","category-biological","category-life-extension","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/240986","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=240986"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/240986\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=240986"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=240986"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=240986"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}