{"id":240722,"date":"2026-07-13T07:09:43","date_gmt":"2026-07-13T12:09:43","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/07\/second-prostate-specific-membrane-antigen-pet-scan-can-change-treatment-for-nearly-half-of-prostate-cancer-patients"},"modified":"2026-07-13T07:09:43","modified_gmt":"2026-07-13T12:09:43","slug":"second-prostate-specific-membrane-antigen-pet-scan-can-change-treatment-for-nearly-half-of-prostate-cancer-patients","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/07\/second-prostate-specific-membrane-antigen-pet-scan-can-change-treatment-for-nearly-half-of-prostate-cancer-patients","title":{"rendered":"Second prostate-specific membrane antigen PET scan can change treatment for nearly half of prostate cancer patients"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/second-prostate-specific-membrane-antigen-pet-scan-can-change-treatment-for-nearly-half-of-prostate-cancer-patients.jpg\"><\/a><\/p>\n<p>A second prostate-specific membrane antigen (PSMA) PET scan changed treatment plans for nearly half of patients whose first scan was negative, according to new research <a href=\"http:\/\/jnm.snmjournals.org\/lookup\/doi\/10.2967\/jnumed.126.272204\" target=\"_blank\">published<\/a> in the July issue of <i>The Journal of Nuclear Medicine.<\/i> Findings from the repeat PSMA scans, which included both local and distant disease, resulted in a change in management for nearly 50% of these patients.<\/p>\n<p>Managing recurrent prostate cancer after first-line treatment, such as prostatectomy or radiation therapy, remains a clinical challenge. Although <a href=\"https:\/\/medicalxpress.com\/news\/2022-06-psma-pet-highlights-prostate-cancer.html?utm_source=embeddings&utm_medium=related&utm_campaign=internal\" rel=\"related\">PSMA PET imaging<\/a> has improved disease detection, 30% of patients still have no detectable disease on initial imaging, even as rising prostate-specific antigen (PSA) levels suggest recurrence. Few studies have examined whether repeating PSMA PET in this situation is worthwhile.<\/p>\n<p>\u201cThere is little information on the utility of repeating a PSMA PET after an initial negative scan,\u201d said Ur Metser, BSc, MD, FRCPC, professor of radiology at the University of Toronto and head of the Division of Molecular Imaging at the Joint Department of Medical Imaging at Princess Margaret Cancer Centre in Toronto. \u201cIn our study, my colleagues and I sought to determine the benefit of a second PSMA PET scan, as well as to assess predictors for positive PSMA PET scans.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A second prostate-specific membrane antigen (PSMA) PET scan changed treatment plans for nearly half of patients whose first scan was negative, according to new research published in the July issue of The Journal of Nuclear Medicine. Findings from the repeat PSMA scans, which included both local and distant disease, resulted in a change in management [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-240722","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/240722","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=240722"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/240722\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=240722"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=240722"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=240722"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}