{"id":240514,"date":"2026-07-09T03:21:14","date_gmt":"2026-07-09T08:21:14","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/07\/new-crispr-method-makes-it-possible-to-control-protein-production-in-cells"},"modified":"2026-07-09T03:21:14","modified_gmt":"2026-07-09T08:21:14","slug":"new-crispr-method-makes-it-possible-to-control-protein-production-in-cells","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/07\/new-crispr-method-makes-it-possible-to-control-protein-production-in-cells","title":{"rendered":"New CRISPR method makes it possible to control protein production in cells"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/new-crispr-method-makes-it-possible-to-control-protein-production-in-cells.jpg\"><\/a><\/p>\n<p>The speed at which a cell produces proteins is a decisive factor in determining whether it divides, specializes or retains its stem cell properties. A team of researchers led by Professor Stefan H. Stricker, professor of epigenetic engineering at LMU\u2019s Biomedical Center and research group leader at Helmholtz Munich, has worked with international partners to demonstrate directly for the first time that the amount of ribosomal RNA (rRNA) directly regulates these processes. Their results were <a href=\"https:\/\/www.science.org\/doi\/10.1126\/science.aeh1348\" target=\"_blank\">published<\/a> in the journal Science.<\/p>\n<p>It has been established for some time that the amount of ribosomal RNA differs among different types of cells and is altered in a number of diseases. But it remained unclear whether these specific characteristics are the cause or merely the result of biological processes.<\/p>\n<p>With the newly developed CRISPR-based method TAPIR (Targeted Activation of Protein Translation), researchers now have access to a tool that can boost the activity of ribosomal genes and, as a result, influence a cell\u2019s protein production. \u201cOur new study shows that targeted activation of rRNA production significantly increases protein synthesis,\u201d explains Stricker, lead author of the publication.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The speed at which a cell produces proteins is a decisive factor in determining whether it divides, specializes or retains its stem cell properties. A team of researchers led by Professor Stefan H. Stricker, professor of epigenetic engineering at LMU\u2019s Biomedical Center and research group leader at Helmholtz Munich, has worked with international partners to [\u2026]<\/p>\n","protected":false},"author":427,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,38,412],"tags":[],"class_list":["post-240514","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-engineering","category-genetics"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/240514","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/427"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=240514"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/240514\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=240514"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=240514"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=240514"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}