{"id":240478,"date":"2026-07-08T20:10:15","date_gmt":"2026-07-09T01:10:15","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/07\/rna-binding-protein-diversity-and-nls-arginines-regulate-fus-mixing-in-mrna-rich-compartments"},"modified":"2026-07-08T20:10:15","modified_gmt":"2026-07-09T01:10:15","slug":"rna-binding-protein-diversity-and-nls-arginines-regulate-fus-mixing-in-mrna-rich-compartments","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/07\/rna-binding-protein-diversity-and-nls-arginines-regulate-fus-mixing-in-mrna-rich-compartments","title":{"rendered":"RNA-binding protein diversity and NLS arginines regulate FUS mixing in mRNA-rich compartments"},"content":{"rendered":"<p style=\"padding-right: 20px\"><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/rna-binding-protein-diversity-and-nls-arginines-regulate-fus-mixing-in-mrna-rich-compartments.jpg\"><\/a><\/p>\n<p>Valenti et al. used the MT bench assay to quantify FUS homotypic\/heterotypic interactions in compartments of heterogeneous compositions in cells. They showed that FUS heterotypic interactions with other RBPs, orchestrated by its disease-related NLS, prevent FUS phase separation independently from nuclear transporters.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Valenti et al. used the MT bench assay to quantify FUS homotypic\/heterotypic interactions in compartments of heterogeneous compositions in cells. They showed that FUS heterotypic interactions with other RBPs, orchestrated by its disease-related NLS, prevent FUS phase separation independently from nuclear transporters.<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-240478","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/240478","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=240478"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/240478\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=240478"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=240478"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=240478"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}