{"id":240159,"date":"2026-07-02T07:06:34","date_gmt":"2026-07-02T12:06:34","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/07\/faulty-calcium-signaling-may-drive-dry-mouth-in-down-syndrome-raising-gum-disease-risk"},"modified":"2026-07-02T07:06:34","modified_gmt":"2026-07-02T12:06:34","slug":"faulty-calcium-signaling-may-drive-dry-mouth-in-down-syndrome-raising-gum-disease-risk","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/07\/faulty-calcium-signaling-may-drive-dry-mouth-in-down-syndrome-raising-gum-disease-risk","title":{"rendered":"Faulty calcium signaling may drive dry mouth in Down syndrome, raising gum disease risk"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/faulty-calcium-signaling-may-drive-dry-mouth-in-down-syndrome-raising-gum-disease-risk.jpg\"><\/a><\/p>\n<p>Researchers at NYU College of Dentistry have uncovered what may be biologically driving oral health issues unique to Down syndrome. Their study, <a href=\"https:\/\/www.cell.com\/cell-reports\/fulltext\/S2211-1247(26)00697-2\" target=\"_blank\">published<\/a> in <i>Cell Reports<\/i>, describes a molecular mechanism\u2014a defect in calcium signaling\u2014behind low saliva production, along with other factors that may contribute to gum disease.<\/p>\n<p>\u201cUnderstanding the processes responsible for low saliva in Down syndrome and developing therapies to restore salivation could have a transformative impact on the oral and overall health of people with Down syndrome,\u201d said Rodrigo Lacruz, professor of molecular pathobiology at NYU College of Dentistry and the study\u2019s senior author.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Researchers at NYU College of Dentistry have uncovered what may be biologically driving oral health issues unique to Down syndrome. Their study, published in Cell Reports, describes a molecular mechanism\u2014a defect in calcium signaling\u2014behind low saliva production, along with other factors that may contribute to gum disease. \u201cUnderstanding the processes responsible for low saliva in [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,1495],"tags":[],"class_list":["post-240159","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-health"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/240159","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=240159"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/240159\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=240159"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=240159"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=240159"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}