{"id":240020,"date":"2026-06-30T14:13:33","date_gmt":"2026-06-30T19:13:33","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/06\/blood-biomarkers-could-measure-response-to-psychotherapy-in-patients-with-depression"},"modified":"2026-06-30T14:13:33","modified_gmt":"2026-06-30T19:13:33","slug":"blood-biomarkers-could-measure-response-to-psychotherapy-in-patients-with-depression","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/06\/blood-biomarkers-could-measure-response-to-psychotherapy-in-patients-with-depression","title":{"rendered":"Blood biomarkers could measure response to psychotherapy in patients with depression"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/blood-biomarkers-could-measure-response-to-psychotherapy-in-patients-with-depression.jpg\"><\/a><\/p>\n<p>Research by the Barcelona Institute for Biomedical Research (IIBB), part of the Spanish National Research Council (CSIC), and the Institut de Recerca Sant Pau (IR Sant Pau) provides some of the first evidence that psychological therapies act as biological stimuli that induce molecular responses measurable through blood biomarkers.<\/p>\n<p>The preliminary study, involving 22 patients with major depressive disorder at Hospital de Sant Pau, reveals that psychotherapy sessions trigger changes in microRNAs\u2014molecules that regulate gene expression in cells\u2014associated with significant improvements in the participants\u2019 cognitive status. The results, <a href=\"https:\/\/www.nature.com\/articles\/s41598-026-55039-1\" target=\"_blank\">published<\/a> in <i>Scientific Reports<\/i>, represent an advance toward monitoring patients\u2019 responses to pharmacological treatments and nonpharmacological therapeutic interventions.<\/p>\n<p>The study, led by Dr. Maria J. Portella (IR Sant Pau) and Dr. Analia Bortolozzi (IIBB-CSIC), with Llu\u00eds Miquel-Rio (IIBB-CSIC) and Dr. Muriel Vicent-Gil (Hospital de Sant Pau) as first authors, focused on major depressive disorder (MDD). This condition is characterized not only by its effects on mood but also by a broad spectrum of cognitive impairments, including difficulties with attention, memory, processing speed and executive function. These symptoms frequently persist despite treatment and severely affect patients\u2019 quality of life.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Research by the Barcelona Institute for Biomedical Research (IIBB), part of the Spanish National Research Council (CSIC), and the Institut de Recerca Sant Pau (IR Sant Pau) provides some of the first evidence that psychological therapies act as biological stimuli that induce molecular responses measurable through blood biomarkers. The preliminary study, involving 22 patients with [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,47],"tags":[],"class_list":["post-240020","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/240020","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=240020"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/240020\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=240020"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=240020"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=240020"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}