{"id":239894,"date":"2026-06-28T23:08:02","date_gmt":"2026-06-29T04:08:02","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/06\/age-identifies-cancer-drivers-hidden-within-the-genome"},"modified":"2026-06-28T23:08:02","modified_gmt":"2026-06-29T04:08:02","slug":"age-identifies-cancer-drivers-hidden-within-the-genome","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/06\/age-identifies-cancer-drivers-hidden-within-the-genome","title":{"rendered":"Age identifies cancer drivers hidden within the genome"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/age-identifies-cancer-drivers-hidden-within-the-genome.jpg\"><\/a><\/p>\n<p>As tissues age, mutant clones carrying driver mutations expand, yet the abundance of these variants in normal tissues suggests that fitness-based selection is often uncoupled from malignancy. Cheek et al. introduce a framework that disentangles clonal success from true carcinogenic potential, showing that fitness and fate are not synonymous.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>As tissues age, mutant clones carrying driver mutations expand, yet the abundance of these variants in normal tissues suggests that fitness-based selection is often uncoupled from malignancy. Cheek et al. introduce a framework that disentangles clonal success from true carcinogenic potential, showing that fitness and fate are not synonymous.<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-239894","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/239894","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=239894"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/239894\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=239894"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=239894"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=239894"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}